Date published: 2025-9-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

Heterobifunctional Crosslinkers

Santa Cruz Biotechnology now offers a broad range of heterobifunctional crosslinkers for use in various applications. Heterobifunctional crosslinkers are versatile chemical reagents that possess two different reactive groups, allowing them to link two distinct molecules or surfaces. These crosslinkers are crucial in scientific research for studying and manipulating molecular interactions, creating conjugates, and developing advanced biomaterials. Researchers utilize heterobifunctional crosslinkers to investigate protein-protein, protein-DNA, and protein-ligand interactions, providing insights into cellular signaling pathways, structural biology, and enzymatic functions. They are also used to immobilize biomolecules on various surfaces for biosensor development, drug delivery systems, and diagnostic assays. The ability to selectively and efficiently join different molecules makes these crosslinkers invaluable for designing complex molecular architectures and enhancing the functionality of biomaterials. By providing a comprehensive selection of high-quality heterobifunctional crosslinkers, Santa Cruz Biotechnology supports cutting-edge research in biochemistry, molecular biology, and materials science. These products enable scientists to achieve precise and reproducible results, driving advancements in our understanding of molecular interactions and the development of innovative biotechnological applications. View detailed information on our available heterobifunctional crosslinkers by clicking on the product name.

Items 51 to 56 of 56 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Maleimide-PEG12-NHS ester

1426151-00-9sc-397277
sc-397277A
50 mg
250 mg
$340.00
$750.00
(0)

Maleimide-PEG12-NHS ester is a versatile heterobifunctional reagent featuring a maleimide moiety that selectively reacts with thiols, creating robust thioether bonds. The NHS ester component provides a rapid and efficient pathway for amine coupling, yielding stable amide linkages. The extended PEG chain enhances solubility and flexibility, facilitating improved molecular interactions and reaction kinetics, making it suitable for diverse bioconjugation strategies and complex biomolecule assembly.

monodisperse Mal-PEG4-NHS-ester

756525-99-2sc-397273
100 mg
$323.00
(0)

Monodisperse Mal-PEG4-NHS-ester is a specialized heterobifunctional linker characterized by its precise molecular weight and uniformity. The NHS ester group enables swift and selective amine coupling, while the maleimide moiety engages thiols, forming stable thioether bonds. Its PEG4 segment enhances solubility and biocompatibility, promoting efficient molecular interactions. This unique combination of functionalities allows for tailored conjugation strategies and optimized reaction dynamics in various applications.

Maleimide-PEG8-NHS ester

756525-93-6sc-397276
sc-397276A
50 mg
250 mg
$206.00
$599.00
(0)

Maleimide-PEG8-NHS ester is a versatile heterobifunctional reagent featuring a polyethylene glycol (PEG) spacer that enhances solubility and flexibility. The NHS ester facilitates rapid and specific reactions with amines, while the maleimide group selectively reacts with thiol-containing compounds, yielding robust thioether linkages. This compound's unique structure promotes efficient conjugation and fine-tuning of molecular interactions, making it ideal for diverse biochemical applications.

[N-(2-Maleimidoethyl]diethylenetriaminepentaacetic Acid, Monoamide

180152-82-3sc-218918
10 mg
$500.00
(0)

N-(2-Maleimidoethyl]diethylenetriaminepentaacetic Acid, Monoamide is a heterobifunctional compound characterized by its dual reactivity. The maleimide moiety enables selective conjugation with thiols, forming stable thioether bonds, while the diethylenetriaminepentaacetic acid component offers multiple coordination sites for metal ions. This unique combination allows for intricate molecular assembly and enhanced stability in complex biochemical environments, facilitating diverse interaction pathways.

2-maleimidoethylamine hydrochloride

134272-64-3sc-265752
sc-265752A
sc-265752B
100 mg
1 g
5 g
$90.00
$311.00
$984.00
(0)

2-Maleimidoethylamine hydrochloride is a heterobifunctional compound characterized by its ability to form stable covalent bonds with thiol groups, enabling selective labeling and cross-linking of biomolecules. Its unique amine and maleimide functionalities facilitate specific interactions, allowing for precise conjugation in complex biochemical environments. The compound's reactivity is influenced by pH and temperature, which can modulate its kinetics, enhancing its utility in various chemical applications.

N-(2-Maleimidoethyl)-6-aminohexanamide, Trifluoroacetic Acid Salt

1185075-13-1sc-218916
10 mg
$300.00
(0)

N-(2-Maleimidoethyl)-6-aminohexanamide, Trifluoroacetic Acid Salt is a heterobifunctional compound distinguished by its ability to engage in selective cross-linking and conjugation reactions. The maleimide group provides a reactive site for thiol attachment, promoting the formation of robust thioether linkages. Meanwhile, the trifluoroacetic acid salt enhances solubility and stability, facilitating efficient reaction kinetics in various environments, thus enabling complex molecular interactions and assemblies.