HCFC1R1 inhibitors are a group of compounds characterized by their ability to modulate the activity of the HCFC1R1 protein. HCFC1R1, or Host Cell Factor 1 Regulator 1, is a protein that functions as a transcriptional co-regulator, playing a role in the regulation of gene expression. Inhibitors belonging to this class interact with HCFC1R1 at various levels, potentially affecting its interaction with transcription factors or its role in chromatin remodeling. These inhibitors can operate through diverse mechanisms, such as disrupting protein-protein interactions, interfering with DNA binding, or affecting the protein's stability.
The chemical structures of HCFC1R1 inhibitors can vary widely, including natural compounds like plant-derived sesquiterpene lactones, cyclic peptides, and antibiotics, as well as synthetic compounds designed for their inhibitory properties. Researchers have investigated these compounds to better understand the cellular processes influenced by HCFC1R1 and its impact on gene regulation. The study of HCFC1R1 inhibitors contributes to a deeper comprehension of gene expression control mechanisms and has potential implications for manipulating cellular responses in various contexts.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Quinacrine, Dihydrochloride | 69-05-6 | sc-204222 sc-204222B sc-204222A sc-204222C sc-204222D | 100 mg 1 g 5 g 200 g 300 g | $46.00 $57.00 $87.00 $3257.00 $4821.00 | 4 | |
An antimalarial drug that has been studied for its potential in inhibiting HCFC1R1 and modulating gene expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
A natural compound found in turmeric with anti-inflammatory and potential anticancer properties. It has been investigated as a HCFC1R1 inhibitor. | ||||||
Oridonin, R. rubescens | 28957-04-2 | sc-202751 | 5 mg | $77.00 | ||
A natural compound found in Rabdosia rubescens, it has shown potential as a HCFC1R1 inhibitor and could have anticancer effects. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $81.00 $306.00 | 32 | |
Another natural compound found in plants like feverfew, which has been studied for its ability to inhibit HCFC1R1 and affect cellular processes. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
A natural antibiotic that can inhibit HCFC1R1 indirectly by disrupting protein folding and degradation. | ||||||
Quinomycin A | 512-64-1 | sc-202306 | 1 mg | $166.00 | 4 | |
A cyclic peptide that can inhibit DNA binding of HCFC1R1, affecting its transcriptional regulatory functions. | ||||||
Thiostrepton | 1393-48-2 | sc-203412 sc-203412A | 1 g 5 g | $117.00 $423.00 | 10 | |
An antibiotic that can disrupt the activity of HCFC1R1 by targeting its interaction with transcription factors. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
An antibiotic that can inhibit transcription by preventing RNA synthesis, which indirectly affects HCFC1R1-regulated processes. | ||||||
Leptomycin B | 87081-35-4 | sc-358688 sc-358688A sc-358688B | 50 µg 500 µg 2.5 mg | $107.00 $416.00 $1248.00 | 35 | |
A natural compound that can inhibit the export of certain proteins, potentially impacting HCFC1R1's functions. | ||||||