Date published: 2026-5-30

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HCFC1R1 Inhibitors

HCFC1R1 inhibitors are a group of compounds characterized by their ability to modulate the activity of the HCFC1R1 protein. HCFC1R1, or Host Cell Factor 1 Regulator 1, is a protein that functions as a transcriptional co-regulator, playing a role in the regulation of gene expression. Inhibitors belonging to this class interact with HCFC1R1 at various levels, potentially affecting its interaction with transcription factors or its role in chromatin remodeling. These inhibitors can operate through diverse mechanisms, such as disrupting protein-protein interactions, interfering with DNA binding, or affecting the protein's stability.

The chemical structures of HCFC1R1 inhibitors can vary widely, including natural compounds like plant-derived sesquiterpene lactones, cyclic peptides, and antibiotics, as well as synthetic compounds designed for their inhibitory properties. Researchers have investigated these compounds to better understand the cellular processes influenced by HCFC1R1 and its impact on gene regulation. The study of HCFC1R1 inhibitors contributes to a deeper comprehension of gene expression control mechanisms and has potential implications for manipulating cellular responses in various contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Quinacrine, Dihydrochloride

69-05-6sc-204222
sc-204222B
sc-204222A
sc-204222C
sc-204222D
100 mg
1 g
5 g
200 g
300 g
$46.00
$57.00
$87.00
$3257.00
$4821.00
4
(2)

An antimalarial drug that has been studied for its potential in inhibiting HCFC1R1 and modulating gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

A natural compound found in turmeric with anti-inflammatory and potential anticancer properties. It has been investigated as a HCFC1R1 inhibitor.

Oridonin, R. rubescens

28957-04-2sc-202751
5 mg
$77.00
(0)

A natural compound found in Rabdosia rubescens, it has shown potential as a HCFC1R1 inhibitor and could have anticancer effects.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$81.00
$306.00
32
(2)

Another natural compound found in plants like feverfew, which has been studied for its ability to inhibit HCFC1R1 and affect cellular processes.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

A natural antibiotic that can inhibit HCFC1R1 indirectly by disrupting protein folding and degradation.

Quinomycin A

512-64-1sc-202306
1 mg
$166.00
4
(1)

A cyclic peptide that can inhibit DNA binding of HCFC1R1, affecting its transcriptional regulatory functions.

Thiostrepton

1393-48-2sc-203412
sc-203412A
1 g
5 g
$117.00
$423.00
10
(1)

An antibiotic that can disrupt the activity of HCFC1R1 by targeting its interaction with transcription factors.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

An antibiotic that can inhibit transcription by preventing RNA synthesis, which indirectly affects HCFC1R1-regulated processes.

Leptomycin B

87081-35-4sc-358688
sc-358688A
sc-358688B
50 µg
500 µg
2.5 mg
$107.00
$416.00
$1248.00
35
(2)

A natural compound that can inhibit the export of certain proteins, potentially impacting HCFC1R1's functions.