GSTM6 inhibitors belong to a class of chemical compounds that have garnered attention in the field of molecular biology and cellular detoxification processes research. These inhibitors are specifically designed to target and modulate the activity of GSTM6, which stands for Glutathione S-transferase Mu 6. GSTM6 is a member of the glutathione S-transferase (GST) family of enzymes, which play crucial roles in cellular detoxification by catalyzing the conjugation of glutathione to a wide range of electrophilic compounds, such as xenobiotics, carcinogens, and endogenous metabolites. This enzymatic reaction enhances the solubility of these toxic molecules, facilitating their elimination from the body and protecting cells from damage.
GSTM6 inhibitors exert their effects by interfering with the enzymatic activity or expression of GSTM6, disrupting its role in the detoxification of harmful compounds. This interference can lead to alterations in the cellular response to xenobiotics and endogenous toxins, \\ impacting the body's ability to detoxify and eliminate harmful substances. Researchers employ GSTM6 inhibitors as valuable tools to investigate the specific roles of GSTM6 in different cellular contexts and to gain insights into the molecular mechanisms governing detoxification processes and their implications for cellular health. While the precise applications and broader implications of GSTM6 inhibitors are subjects of ongoing research, their utility in elucidating the complexities of cellular detoxification and its impact on overall health is of paramount importance in advancing our understanding of molecular and cell biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $53.00 $89.00 | 7 | |
Alters the activity of various enzymes and transcription factors, potentially influencing the expression of GSTM6. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A well-known stimulant that affects multiple signaling pathways, which may incidentally alter the transcription of genes like GSTM6. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $89.00 $228.00 | ||
Influences numerous cellular pathways and may downregulate GSTs as part of its complex interactions within the cell. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
A polyphenol thought to influence phase II detoxifying enzymes, which might include modulation of GSTM6 expression. | ||||||
Sodium (meta)arsenite | 7784-46-5 | sc-250986 sc-250986A | 100 g 1 kg | $108.00 $780.00 | 3 | |
Affects cellular signaling and gene expression; it might lead to the reduced expression of genes like GSTM6. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
Has the potential to alter protein expression profiles and could affect GSTM6 expression. | ||||||
Cadmium chloride, anhydrous | 10108-64-2 | sc-252533 sc-252533A sc-252533B | 10 g 50 g 500 g | $56.00 $183.00 $352.00 | 1 | |
A heavy metal that interferes with cellular processes and could reduce the expression of detoxifying enzymes like GSTM6. | ||||||
Benzene | 71-43-2 | sc-239290 | 1 L | $79.00 | ||
A solvent known to affect the blood and bone marrow, could alter the transcription of genes including GSTM6. | ||||||
Methoxychlor | 72-43-5 | sc-253009 | 100 mg | $36.00 | ||
A pesticide that acts as an endocrine disruptor and might affect the expression of enzymes like GSTM6 through hormonal pathways. | ||||||