Date published: 2026-5-30

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GSTM6 Inhibitors

GSTM6 inhibitors belong to a class of chemical compounds that have garnered attention in the field of molecular biology and cellular detoxification processes research. These inhibitors are specifically designed to target and modulate the activity of GSTM6, which stands for Glutathione S-transferase Mu 6. GSTM6 is a member of the glutathione S-transferase (GST) family of enzymes, which play crucial roles in cellular detoxification by catalyzing the conjugation of glutathione to a wide range of electrophilic compounds, such as xenobiotics, carcinogens, and endogenous metabolites. This enzymatic reaction enhances the solubility of these toxic molecules, facilitating their elimination from the body and protecting cells from damage.

GSTM6 inhibitors exert their effects by interfering with the enzymatic activity or expression of GSTM6, disrupting its role in the detoxification of harmful compounds. This interference can lead to alterations in the cellular response to xenobiotics and endogenous toxins, \\ impacting the body's ability to detoxify and eliminate harmful substances. Researchers employ GSTM6 inhibitors as valuable tools to investigate the specific roles of GSTM6 in different cellular contexts and to gain insights into the molecular mechanisms governing detoxification processes and their implications for cellular health. While the precise applications and broader implications of GSTM6 inhibitors are subjects of ongoing research, their utility in elucidating the complexities of cellular detoxification and its impact on overall health is of paramount importance in advancing our understanding of molecular and cell biology.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$53.00
$89.00
7
(1)

Alters the activity of various enzymes and transcription factors, potentially influencing the expression of GSTM6.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$33.00
$67.00
$97.00
$192.00
$775.00
13
(1)

A well-known stimulant that affects multiple signaling pathways, which may incidentally alter the transcription of genes like GSTM6.

Arsenic(III) oxide

1327-53-3sc-210837
sc-210837A
250 g
1 kg
$89.00
$228.00
(0)

Influences numerous cellular pathways and may downregulate GSTs as part of its complex interactions within the cell.

Ellagic Acid, Dihydrate

476-66-4sc-202598
sc-202598A
sc-202598B
sc-202598C
500 mg
5 g
25 g
100 g
$58.00
$95.00
$245.00
$727.00
8
(1)

A polyphenol thought to influence phase II detoxifying enzymes, which might include modulation of GSTM6 expression.

Sodium (meta)arsenite

7784-46-5sc-250986
sc-250986A
100 g
1 kg
$108.00
$780.00
3
(2)

Affects cellular signaling and gene expression; it might lead to the reduced expression of genes like GSTM6.

Gallotannin

1401-55-4sc-202619
sc-202619A
sc-202619B
sc-202619C
sc-202619D
sc-202619E
sc-202619F
1 g
10 g
100 g
250 g
1 kg
2.5 kg
5 kg
$26.00
$37.00
$67.00
$78.00
$234.00
$536.00
$983.00
12
(1)

Has the potential to alter protein expression profiles and could affect GSTM6 expression.

Cadmium chloride, anhydrous

10108-64-2sc-252533
sc-252533A
sc-252533B
10 g
50 g
500 g
$56.00
$183.00
$352.00
1
(1)

A heavy metal that interferes with cellular processes and could reduce the expression of detoxifying enzymes like GSTM6.

Benzene

71-43-2sc-239290
1 L
$79.00
(0)

A solvent known to affect the blood and bone marrow, could alter the transcription of genes including GSTM6.

Methoxychlor

72-43-5sc-253009
100 mg
$36.00
(0)

A pesticide that acts as an endocrine disruptor and might affect the expression of enzymes like GSTM6 through hormonal pathways.