GSDMC3 Inhibitors
GSDMC3 inhibitors belong to a specific class of chemical compounds designed for the purpose of modulating the activity of the Gasdermin C3 (GSDMC3) protein. Gasdermins are a family of proteins that have garnered significant attention in recent years due to their pivotal roles in cellular processes, particularly in cell death and inflammation regulation. GSDMC3 is a member of the Gasdermin family, and its precise functions are still a subject of ongoing research. The primary objective of GSDMC3 inhibitors is to interact with the GSDMC3 protein in a selective manner, potentially influencing its activity and subsequently impacting downstream cellular processes.
GSDMC3 inhibitors are typically comprised of small molecules or chemical compounds designed to bind to GSDMC3, either at its active site or at allosteric sites. This interaction can lead to the modulation of GSDMC3's behavior, potentially affecting its ability to form membrane pores, participate in cell death pathways, or execute other cellular functions. Researchers are primarily focused on unraveling the biological roles and mechanisms of GSDMC3, as well as how inhibiting its activity with these compounds may provide insights into various cellular processes. The development of GSDMC3 inhibitors represents an ongoing area of research within the field of molecular pharmacology and biochemistry, contributing to our understanding of cell biology and the functions of Gasdermin family proteins.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate various signaling pathways, including NF-κB, which might lead to reduced expression of gasdermin proteins involved in inflammatory processes. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane is known to affect the NRF2 pathway and might influence the expression of various genes, including those in the inflammation and cell death pathways. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to modulate multiple cellular pathways, potentially affecting the expression of genes involved in cell death and inflammation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
As a DNA methyltransferase inhibitor, 5-Azacytidine can alter gene expression patterns, potentially affecting the expression of inflammatory genes. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
SAHA is a histone deacetylase (HDAC) inhibitor and can broadly alter gene expression, which may include genes encoding for gasdermin proteins. | ||||||
Pyrrolidinedithiocarbamic acid ammonium salt | 5108-96-3 | sc-203224 sc-203224A | 5 g 25 g | $33.00 $64.00 | 11 | |
PDTC is a NF-κB inhibitor and may alter the expression of genes involved in inflammation and cell death pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can modulate various signaling pathways, including those related to inflammation, potentially impacting the expression of related genes. | ||||||
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
Apigenin may influence gene expression by modulating transcription factor activity, such as NF-κB, which is often involved in regulating genes associated with inflammation. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Anacardic Acid inhibits histone acetyltransferases, potentially altering the expression of genes, including those involved in inflammation and pyroptosis. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is known to affect multiple signaling pathways and may indirectly modulate the expression of genes involved in inflammatory responses. | ||||||