group IVC sPLA2 Activators
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Arachidonic Acid (20:4, n-6) | 506-32-1 | sc-200770 sc-200770A sc-200770B | 100 mg 1 g 25 g | $92.00 $240.00 $4328.00 | 9 | |
As a fatty acid, arachidonic acid serves as a substrate for Group IVC sPLA2, thereby leading to its activation. Group IVC sPLA2 catalyzes the hydrolysis of phospholipids releasing arachidonic acid, which suggests that the presence of this substrate could enhance the enzymatic activity of Group IVC sPLA2. | ||||||
L-α-Lecithin, Egg Yolk, Highly Purified | 8002-43-5 | sc-203096 | 250 mg | $135.00 | ||
Phosphatidylserine is a phospholipid component of the cell membrane that can be a specific substrate for Group IVC sPLA2. The availability of such substrates in the vicinity of the enzyme activates its hydrolytic function on the cellular membranes, thereby increasing Group IVC sPLA2 activity. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
Prostaglandin E2 is a bioactive lipid product of arachidonic acid metabolism. While it does not directly activate Group IVC sPLA2, its presence indicates active lipid signaling, which could be indicative of conditions that favor Group IVC sPLA2 activity, such as the presence of substrate or a cellular environment that promotes the enzyme's activity. | ||||||
PAF C-16 | 74389-68-7 | sc-201009 sc-201009A | 5 mg 25 mg | $131.00 $300.00 | 10 | |
Although typically known as a potent lipid mediator, platelet-activating factor may alter cellular membranes' composition or signaling environment in a way that promotes the activity of Group IVC sPLA2, possibly by increasing the availability of substrates or by inducing a cellular state that necessitates enhanced lipid signaling and remodeling activity of the enzyme. | ||||||
Melittin | 37231-28-0 | sc-200868 sc-200868A sc-200868B | 500 µg 1 mg 10 mg | $196.00 $339.00 $787.00 | 2 | |
Melittin is a peptide that can insert into lipid membranes and disrupt their structure. This disruption could lead to an increased accessibility of phospholipid substrates to Group IVC sPLA2, potentially enhancing the enzyme's activity. | ||||||
Oleic Acid | 112-80-1 | sc-200797C sc-200797 sc-200797A sc-200797B | 1 g 10 g 100 g 250 g | $37.00 $104.00 $580.00 $1196.00 | 10 | |
Oleic acid is a monounsaturated fatty acid that is a component of phospholipids. When integrated into cellular membranes, it may influence the fluidity and structure of the membrane, potentially making the membrane phospholipids more accessible to Group IVC sPLA2 and thereby activating the enzyme. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine-1-phosphate is a signaling sphingolipid that may influence numerous cellular pathways, including those regulating phospholipase activity. While not a direct activator, the presence of sphingosine-1-phosphate could signal a cellular environment that promotes the hydrolytic action of Group IVC sPLA2 on membrane phospholipids. | ||||||