GMPPB Activators
GMPPB Activators refer to a class of compounds that facilitate the activity of GMPPB by supporting the biosynthesis and availability of its substrates or by providing necessary cofactors for its enzymatic function. This support can be direct, as in the case of mannose and GTP, which are the immediate substrates for the GMPPB-catalyzed reaction, or indirect, such as through the provision of micronutrients like magnesium and manganese that serve as essential cofactors for enzymatic activity. Other compounds in this class, like Vitamin C and folic acid, play roles in enhancing the cellular levels of GTP by participating in metabolic pathways that contribute to nucleotide synthesis.
Compounds such as ATP and ribose-5-phosphate contribute to the pool of precursors necessary for GTP synthesis, thus indirectly supporting the function of GMPPB. Moreover, by influencing the cellular metabolic state, compounds like NAD+, glutamine, and cobalamin create an intracellular environment that is conducive to the enzymatic activity of GMPPB.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $101.00 $158.00 | 1 | |
Mannose is a substrate for the GMPPB enzyme. By increasing intracellular mannose levels, the production of GDP-mannose is likely to be enhanced, thus supporting the enzymatic function of GMPPB. | ||||||
Magnesium sulfate anhydrous | 7487-88-9 | sc-211764 sc-211764A sc-211764B sc-211764C sc-211764D | 500 g 1 kg 2.5 kg 5 kg 10 kg | $45.00 $68.00 $160.00 $240.00 $410.00 | 3 | |
Magnesium ions serve as cofactors for many enzymes, including kinases and phosphorylases. As such, magnesium sulfate can supply the necessary Mg2+ ions that are required for GMPPB catalytic activity. | ||||||
Manganese(II) sulfate monohydrate | 10034-96-5 | sc-203130 sc-203130A | 100 g 500 g | $40.00 $105.00 | ||
Manganese ions can act as cofactors for various enzymes, potentially including GMPPB. By providing Mn2+, Manganese(II) sulfate may indirectly support the catalytic efficiency of GMPPB. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Ascorbic acid can enhance the biosynthesis of GTP, the substrate of GMPPB, through its role in cellular metabolism and by serving as a cofactor for various biosynthetic enzymes. This, in turn, can support the activity of GMPPB. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $56.00 $186.00 $296.00 $655.00 $2550.00 $3500.00 $10500.00 | 4 | |
NAD+ is a cofactor in redox reactions and also plays a role in ADP-ribose transfer reactions. An adequate pool of NAD+ can enhance cellular metabolism and the biosynthesis of GTP, indirectly supporting GMPPB function. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is essential for the synthesis of purines and pyrimidines, which are necessary for the production of GTP. By supporting nucleotide synthesis, folic acid can help maintain a supply of GTP for GMPPB activity. | ||||||
Vitamin B12 | 68-19-9 | sc-296695 sc-296695A sc-296695B sc-296695C sc-296695D sc-296695E | 100 mg 1 g 5 g 25 g 100 g 1 kg | $39.00 $55.00 $204.00 $877.00 $3414.00 $9180.00 | 2 | |
Cobalamin is a cofactor in various cellular processes including the synthesis of methionine and S-adenosylmethionine, which can influence purine and pyrimidine synthesis. By ensuring effective metabolic flow, cobalamin can indirectly support the synthesis of GTP, a substrate for GMPPB. | ||||||
Inosine | 58-63-9 | sc-295182 sc-295182A | 1 g 5 g | $59.00 $90.00 | ||
Inosine can be metabolized into various nucleotides, including GTP. By providing inosine, a pool of nucleotides for GTP synthesis can be ensured, indirectly supporting GMPPB activity. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP is a key molecule in energy transfer and also serves as a phosphate donor in the synthesis of GTP. An ample supply of ATP ensures the availability of phosphate groups necessary for GTP synthesis, indirectly enhancing the activity of GMPPB. | ||||||
L-Glutamine | 56-85-9 | sc-391013 sc-391013C sc-391013A sc-391013D sc-391013B | 100 g 250 g 1 kg 5 kg 10 kg | $36.00 $46.00 $97.00 $372.00 $719.00 | 2 | |
Glutamine provides nitrogen for many biosynthetic processes, including nucleotide biosynthesis. By providing the nitrogen source, glutamine ensures the synthesis of GTP, indirectly supporting GMPPB activity. | ||||||