Gm14496, a predicted gene in Mus musculus (house mouse), is anticipated to play a role in G protein-coupled receptor (GPCR) activity and is predicted to be an integral component of the plasma membrane. GPCRs are essential cell membrane proteins involved in signal transduction, responding to various extracellular molecules and initiating intracellular signaling cascades. The activation of Gm14496 primarily revolves around its role as a GPCR. GPCRs are activated by binding to specific ligands, which can be endogenous molecules like neurotransmitters (e.g., dopamine, serotonin) or hormones (e.g., adrenaline), as well as exogenous compounds (e.g., drugs). Upon ligand binding, GPCRs initiate signaling pathways that can influence a wide range of cellular processes. In the case of Gm14496, ligand binding to its GPCR domain leads to the activation of downstream signaling pathways, which can impact cellular responses related to its integral role in the plasma membrane.
In summary, Gm14496's activation is intricately linked to its function as a GPCR, responding to various ligands that bind to it and initiating signaling cascades that modulate cellular processes. These ligands include neurotransmitters, hormones, and other molecules that directly stimulate Gm14496's GPCR activity. Understanding the specific ligands and pathways that activate Gm14496 is crucial for unraveling its role in cell signaling and membrane function. Further research is needed to fully elucidate the precise mechanisms and functional significance of Gm14496 in mouse biology.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Adenosine | 58-61-7 | sc-291838 sc-291838A sc-291838B sc-291838C sc-291838D sc-291838E sc-291838F | 1 g 5 g 100 g 250 g 1 kg 5 kg 10 kg | $33.00 $47.00 $294.00 $561.00 $1020.00 $2550.00 $4590.00 | 1 | |
Adenosine, an endogenous nucleoside, can activate G protein-coupled receptors (GPCRs). It may directly stimulate Gm14496 by binding to its GPCR, triggering downstream signaling cascades and altering cellular responses associated with Gm14496's role as a GPCR. | ||||||
Dopamine | 51-61-6 | sc-507336 | 1 g | $290.00 | ||
Dopamine acts on dopamine receptors, a class of GPCRs. It may directly activate Gm14496 by binding to its dopamine receptor, initiating signaling pathways that are characteristic of GPCRs, potentially enhancing Gm14496 activity in the plasma membrane. | ||||||
3-(2-Aminoethyl)-1H-indol-5-ol | 50-67-9 | sc-298707 | 1 g | $520.00 | 3 | |
3-(2-Aminoethyl)-1H-indol-5-ol, through its interaction with serotonin receptors (GPCRs), may directly stimulate Gm14496. Serotonin receptor activation initiates GPCR-related signaling cascades, impacting cellular processes that are associated with Gm14496's role in the plasma membrane. | ||||||
Histamine, free base | 51-45-6 | sc-204000 sc-204000A sc-204000B | 1 g 5 g 25 g | $92.00 $277.00 $969.00 | 7 | |
Histamine interacts with histamine receptors (GPCRs) and may directly activate Gm14496. Histamine receptor activation triggers GPCR-associated pathways, potentially enhancing Gm14496 activity in the plasma membrane and promoting its function as a GPCR. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $40.00 $102.00 $197.00 $1739.00 $16325.00 | ||
(-)-Epinephrine acts on adrenergic receptors, a type of GPCR. It may directly stimulate Gm14496 by binding to its adrenergic receptor, initiating signaling cascades typical of GPCRs, potentially amplifying Gm14496's activity in the integral component of the plasma membrane. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $291.00 $566.00 | ||
L-Glutamic Acid acts on glutamate receptors, some of which are GPCRs. It may directly activate Gm14496 by binding to its glutamate receptor, triggering GPCR-associated signaling cascades, potentially promoting Gm14496 activity in the integral component of the plasma membrane. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $56.00 $156.00 $270.00 $665.00 | 37 | |
Prostaglandin E2 (PGE2) can activate GPCRs. It may directly stimulate Gm14496 by binding to its GPCR, initiating downstream signaling pathways characteristic of GPCRs, potentially influencing cellular responses associated with Gm14496's role in the plasma membrane. | ||||||
Angiotensin II, Human | 4474-91-3 | sc-363643 sc-363643A sc-363643B sc-363643C | 1 mg 5 mg 25 mg 100 mg | $50.00 $75.00 $260.00 $505.00 | 3 | |
Angiotensin II activates angiotensin receptors, a class of GPCRs. It may directly activate Gm14496 by binding to its angiotensin receptor, initiating GPCR-related signaling cascades that impact cellular processes associated with Gm14496's function in the plasma membrane. | ||||||
L-Noradrenaline | 51-41-2 | sc-357366 sc-357366A | 1 g 5 g | $320.00 $475.00 | 3 | |
L-Noradrenaline acts on adrenergic receptors, a class of GPCRs. It may directly stimulate Gm14496 by binding to its adrenergic receptor, initiating GPCR-associated pathways, potentially enhancing Gm14496 activity in the integral component of the plasma membrane. | ||||||
Oxytocin acetate salt | 50-56-6 | sc-279938 sc-279938A sc-279938B sc-279938C sc-279938D sc-279938E | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $59.00 $176.00 $330.00 $650.00 $950.00 $1800.00 | 4 | |
Oxytocin acetate salt activates oxytocin receptors, which are GPCRs. It may directly activate Gm14496 by binding to its oxytocin receptor, initiating GPCR-related signaling pathways that influence cellular responses associated with Gm14496's role in the plasma membrane. |