Date published: 2025-9-20

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glypican-3 Antibodies

Santa Cruz Biotechnology features a diverse variety of glypican-3 monoclonal antibodies for research in understanding glypican-3's role in various biological processes. glypican-3 Antibodies are validated for multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Glypican-3 is a heparan sulfate proteoglycan with essential functions in cell growth, differentiation, and signaling pathway regulation. Research has shown glypican-3's significance in cancer development, particularly in tumor growth and metastasis, establishing it as a potential biomarker and therapeutic target in various malignancies. Investigating glypican-3 functions continues to reveal important insights into developmental processes and disease mechanisms. Glypican-3 expression patterns can be effectively studied using specific conjugates, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC). Advanced research techniques help uncover new aspects of glypican-3's biological significance and potential therapeutic applications. Current studies focus on understanding glypican-3's role in cellular signaling and its impact on disease progression. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of glypican-3's role in human health and disease.

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glypican-3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

glypican-3 Antibody (F-3)

sc-390587mouse IgM κ48-74 (h)WB, IP, IF, ELISAm, r, h
5
(3)

glypican-3 Antibody (1G12)

sc-65443mouse IgG1510-580 (h)WB, IP, IF, IHC(P)h
30
(5)

glypican-3 Antibody (H-10)

sc-377266mouse IgG2a κ303-464 (h)WB, IP, IF, ELISAm, r, h

new

(3)

glypican-3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

glypican-3 CRISPR/Cas9 KO Plasmid (h)

sc-400256hGene KnockoutGFP0
(0)

glypican-3 HDR Plasmid (h)

sc-400256-HDRhHomology Directed RepairPuromycin0
(0)

glypican-3 Double Nickase Plasmid (h)

sc-400256-NIChGene KnockoutPuromycin0
(0)

glypican-3 Double Nickase Plasmid (h2)

sc-400256-NIC-2hGene KnockoutPuromycin0
(0)

glypican-3 CRISPR/Cas9 KO Plasmid (m)

sc-420639mGene KnockoutGFP0
(0)

glypican-3 HDR Plasmid (m)

sc-420639-HDRmHomology Directed RepairPuromycin0
(0)

glypican-3 Double Nickase Plasmid (m)

sc-420639-NICmGene KnockoutPuromycin0
(0)

glypican-3 Double Nickase Plasmid (m2)

sc-420639-NIC-2mGene KnockoutPuromycin0
(0)

glypican-3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

glypican-3 CRISPR Activation Plasmid (h)

sc-400256-ACThGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 CRISPR Activation Plasmid (h2)

sc-400256-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 Lentiviral Activation Particles (h)

sc-400256-LAChGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 Lentiviral Activation Particles (h2)

sc-400256-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 CRISPR Activation Plasmid (m)

sc-420639-ACTmGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 CRISPR Activation Plasmid (m2)

sc-420639-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 Lentiviral Activation Particles (m)

sc-420639-LACmGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 Lentiviral Activation Particles (m2)

sc-420639-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

glypican-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

glypican-3 siRNA (h)

sc-40640hGene SilencingN/A
1
(0)

glypican-3 shRNA Plasmid (h)

sc-40640-SHhGene SilencingPuromycin
1
(0)

glypican-3 shRNA (h) Lentiviral Particles

sc-40640-VhGene SilencingPuromycin
1
(0)

glypican-3 siRNA (m)

sc-40641mGene SilencingN/A0
(0)

glypican-3 shRNA Plasmid (m)

sc-40641-SHmGene SilencingPuromycin0
(0)

glypican-3 shRNA (m) Lentiviral Particles

sc-40641-VmGene SilencingPuromycin0
(0)