Date published: 2025-12-9

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 31 to 40 of 344 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

(S)-2-Pyridylthio Cysteamine Hydrochloride

83578-21-6sc-220057
100 mg
$337.00
(0)

(S)-2-Pyridylthio Cysteamine Hydrochloride serves as an effective crosslinker, exhibiting remarkable reactivity due to its thiol and pyridine functionalities. The compound engages in nucleophilic attack, facilitating the formation of covalent bonds with electrophilic sites in polymers. Its unique steric and electronic properties enhance reaction kinetics, promoting efficient network formation. This results in improved mechanical strength and stability in crosslinked materials, making it a versatile agent in various applications.

3-(Boc-amino)propyl bromide

83948-53-2sc-231352
500 mg
$71.00
(0)

3-(Boc-amino)propyl bromide serves as an effective crosslinker due to its reactivity with nucleophiles, enabling the formation of stable covalent bonds. The presence of the Boc (tert-butyloxycarbonyl) protecting group enhances its selectivity in reactions, allowing for controlled polymerization pathways. Its bromide moiety facilitates rapid reaction kinetics, promoting efficient crosslinking in various polymer matrices. This compound's unique structure contributes to tailored mechanical properties in the resulting networks.

1,2-Ethanediyl Bismethanethiosulfonate

55-95-8sc-208746
25 mg
$395.00
3
(1)

1,2-Ethanediyl Bismethanethiosulfonate functions as an effective crosslinker, exhibiting remarkable reactivity due to its bismethanethiosulfonate groups. These groups facilitate the formation of covalent bonds with nucleophilic sites in polymers, enhancing structural integrity. The compound's unique ability to create three-dimensional networks allows for tailored mechanical properties and improved thermal stability. Its reaction kinetics are influenced by environmental factors, enabling precise control over crosslink density and material performance.

DCC

538-75-0sc-239713
sc-239713A
25 g
100 g
$71.00
$204.00
3
(1)

DCC, a potent crosslinker, facilitates the formation of stable covalent bonds through its reactive N-hydroxysuccinimide ester functionality. This enables efficient coupling reactions with amines, enhancing polymer network formation. Its unique reactivity profile allows for rapid reaction kinetics, promoting efficient crosslinking under mild conditions. Additionally, DCC's ability to stabilize intermediates through transient interactions can influence the overall architecture of macromolecular structures, leading to tailored material properties.

N,N′-(1,2-Dihydroxyethylene)bis-acrylamide

868-63-3sc-215503
sc-215503A
5 g
25 g
$186.00
$643.00
(0)

N,N'-(1,2-Dihydroxyethylene)bis-acrylamide serves as an effective crosslinker, facilitating the formation of three-dimensional polymer networks through its reactive acrylamide groups. This compound exhibits a unique ability to enhance mechanical strength and thermal stability in polymer matrices. Its dual hydroxyl groups promote hydrogen bonding, leading to improved adhesion and compatibility with various substrates. The reaction kinetics are favorable, allowing for rapid crosslinking under mild conditions, which is advantageous for diverse applications.

6-Mercapto-1-hexanol

1633-78-9sc-252298
sc-252298A
5 ml
25 ml
$87.00
$293.00
(1)

6-Mercapto-1-hexanol serves as a versatile crosslinker, characterized by its long hydrocarbon chain that enhances flexibility in polymer networks. The thiol group enables efficient formation of covalent bonds, promoting stability and durability in composite materials. Its unique reactivity allows for rapid crosslinking under mild conditions, while the hydrophobic tail contributes to phase separation, improving mechanical properties and thermal resistance in various applications.

N-Z-1,5-pentanediamine hydrochloride

18807-74-4sc-253132
500 mg
$106.00
(0)

N-Z-1,5-pentanediamine hydrochloride serves as an effective crosslinker due to its dual amine groups, which engage in robust hydrogen bonding and ionic interactions. This compound promotes the formation of stable networks through its ability to react with various functional groups, enhancing the structural integrity of polymers. Its hydrophilic nature contributes to improved solubility and dispersion in aqueous systems, facilitating uniform crosslinking and optimizing material performance.

4-Maleimidobutyric Acid

57078-98-5sc-210100
sc-210100A
sc-210100B
sc-210100C
sc-210100D
1 g
10 g
50 g
100 g
500 g
$290.00
$1850.00
$3200.00
$5200.00
$16500.00
2
(0)

4-Maleimidobutyric Acid serves as an effective crosslinker, characterized by its maleimide functional group that readily engages in thiol-ene click reactions. This reactivity facilitates the formation of robust covalent bonds with thiol-containing compounds, promoting the development of complex three-dimensional structures. Its flexible linker enhances spatial arrangement, allowing for tailored mechanical properties and improved stability in polymer matrices, making it a key player in material science applications.

DTME

71865-37-7sc-214925A
sc-214925
sc-214925B
sc-214925C
sc-214925D
5 mg
10 mg
25 mg
50 mg
100 mg
$199.00
$331.00
$556.00
$1122.00
$2045.00
(0)

DTME is a versatile crosslinker characterized by its ability to form robust covalent bonds through its reactive functional groups. This compound exhibits rapid reaction kinetics, enabling efficient network formation in polymer matrices. Its unique structure promotes strong intermolecular interactions, enhancing mechanical properties and thermal stability of the resulting materials. Additionally, DTME's compatibility with various substrates allows for tailored modifications, expanding its utility in diverse applications.

N,N′-Disuccinimidyl carbonate

74124-79-1sc-253161
5 g
$93.00
(0)

N,N'-Disuccinimidyl carbonate serves as a versatile crosslinker, facilitating the formation of stable amide bonds through its reactive carbonate groups. This compound exhibits a unique ability to engage in selective reactions with primary amines, promoting efficient polymerization and network formation. Its reactivity is influenced by the presence of the succinimidyl moiety, which enhances the kinetics of crosslinking, allowing for rapid and controlled assembly of complex structures.