Date published: 2026-2-3

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 261 to 270 of 344 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

N-Dihydrocinnamoylaminocaproic Acid, N-Hydroxysuccinimide Ester

334616-48-7sc-219147
10 mg
$300.00
(0)

N-Dihydrocinnamoylaminocaproic Acid, N-Hydroxysuccinimide Ester serves as an effective crosslinker, exhibiting robust reactivity through its N-hydroxysuccinimide moiety, which facilitates amine coupling. This compound promotes the formation of stable covalent bonds, enhancing structural integrity in polymer networks. Its unique ability to engage in selective reactions with primary amines allows for tailored modifications, making it a valuable tool in material science for creating complex architectures.

1,6-Hexane-bis-[3-(2-pyridyldithio)propionamide]

359435-46-4sc-208807
25 mg
$300.00
(0)

1,6-Hexane-bis-[3-(2-pyridyldithio)propionamide] functions as an effective crosslinker, distinguished by its dual pyridyldithio groups that facilitate thiol-disulfide exchange reactions. This compound exhibits a unique ability to form stable crosslinked networks through selective interactions with thiol groups, enhancing mechanical properties and thermal stability. Its structural design allows for tailored reaction kinetics, enabling precise control over the degree of crosslinking and material characteristics.

11-Maleimidoundecanoic Acid Hydrazide

359436-62-7sc-208849
10 mg
$330.00
(0)

11-Maleimidoundecanoic Acid Hydrazide serves as a versatile crosslinker characterized by its hydrazide functionality, which enables robust covalent bonding through nucleophilic attack on electrophilic sites. The long aliphatic chain enhances solubility and flexibility, promoting effective network formation. Its unique reactivity allows for selective crosslinking under mild conditions, facilitating the development of materials with tailored mechanical properties and enhanced stability.

2-[2-(Boc-amino)ethoxy]ethoxyacetic acid (dicyclohexylammonium) salt

560088-79-1sc-287660
500 mg
$262.00
(0)

2-[2-(Boc-amino)ethoxy]ethoxyacetic acid (dicyclohexylammonium) salt serves as an effective crosslinker, exhibiting strong hydrogen bonding capabilities that facilitate the formation of robust networks. Its dual functional groups enable versatile interactions with various substrates, enhancing polymer stability. The compound's unique steric hindrance influences reaction rates, while its solubility profile allows for tailored processing conditions, optimizing crosslinking efficiency in diverse applications.

N-(3-Trifluoroethanesulfonyloxypropyl)anthraquinone-2-carboxamide

661461-84-3sc-218940
25 mg
$300.00
(0)

N-(3-Trifluoroethanesulfonyloxypropyl)anthraquinone-2-carboxamide serves as an effective crosslinker, distinguished by its anthraquinone moiety that facilitates π-π stacking interactions. This compound exhibits unique reactivity through its sulfonate group, promoting rapid crosslinking kinetics under mild conditions. Its ability to form stable covalent bonds enhances the mechanical properties of polymer matrices, leading to improved thermal stability and chemical resistance in the final products.

O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine

680622-70-2sc-219457
1 mg
$330.00
(0)

O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine serves as a specialized crosslinker, notable for its trifluoroacetamido group that enhances electrophilic reactivity. This compound engages in selective interactions with nucleophiles, promoting efficient covalent bond formation. Its unique structural features enable tailored reaction kinetics, allowing for precise control over crosslink density and network architecture, which is essential for developing advanced materials with specific mechanical properties.

4-(Maleimidomethyl)cyclohexane-1-carbonyl-1-(tert-butyl)carbazate

887406-71-5sc-216696
25 mg
$330.00
(0)

4-(Maleimidomethyl)cyclohexane-1-carbonyl-1-(tert-butyl)carbazate functions as an effective crosslinker, distinguished by its maleimide functionality that enables specific conjugation with thiol groups. This compound exhibits a unique cyclohexane structure, which contributes to its steric hindrance, enhancing selectivity in crosslinking reactions. The tert-butyl group imparts hydrophobic characteristics, influencing solubility and interaction dynamics in various environments, leading to robust and stable polymer networks.

16-Methanethiosulfonyl Hexadecanoic Acid

887406-81-7sc-213617
10 mg
$360.00
(0)

16-Methanethiosulfonyl Hexadecanoic Acid serves as a versatile crosslinker characterized by its unique thiosulfonate functionality, which enables robust covalent bonding with thiol groups. The long hydrophobic carbon chain enhances membrane permeability and promotes self-assembly in lipid environments. Its distinct reaction kinetics allow for controlled crosslinking under mild conditions, making it suitable for creating stable networks in various polymeric systems.

N-Succinimidyloxycarbonylheptyl Methanethiosulfonate

887407-50-3sc-219229
10 mg
$330.00
(0)

N-Succinimidyloxycarbonylheptyl Methanethiosulfonate serves as a versatile crosslinker characterized by its unique methanethiosulfonate moiety, which engages in selective thiol-disulfide exchange reactions. This property allows for the formation of stable covalent bonds under mild conditions. The heptyl chain contributes to hydrophobic interactions, enhancing solubility in various environments. Its distinct reactivity profile and favorable kinetics facilitate efficient crosslinking in diverse biochemical and material contexts.

N-Succinimidyloxycarbonylpentadecyl Methanethiosulfonate

887407-52-5sc-219230
10 mg
$280.00
(0)

N-Succinimidyloxycarbonylpentadecyl Methanethiosulfonate is a specialized crosslinker featuring a long pentadecyl chain that enhances hydrophobic interactions, promoting stability in complex environments. Its methanethiosulfonate group enables rapid thiol-reactive crosslinking, allowing for precise control over polymer network formation. The compound's unique reactivity and favorable kinetics facilitate efficient integration into various matrices, making it suitable for diverse applications in material science and biochemistry.