GAP1-InsP4 BP Activators
GAP1-InsP4 BP activators belong to a distinctive chemical class characterized by their ability to modulate the activity of the inositol polyphosphate 5-phosphatase enzyme known as GAP1 (GTPase-activating protein for phospholipase C-beta 1) in the presence of inositol 1,4,5-trisphosphate (InsP4). This class of compounds plays a pivotal role in regulating intracellular signaling pathways by fine-tuning the concentration of InsP4, a key secondary messenger molecule involved in cell signaling. The activators specifically interact with GAP1 and enhance its catalytic activity towards InsP4, thereby influencing downstream cellular responses.
At the molecular level, GAP1-InsP4 BP activators exhibit a unique mechanism of action. They are thought to bind to specific binding sites on GAP1, inducing conformational changes that facilitate the efficient hydrolysis of InsP4 into inositol 1,3,4-trisphosphate (InsP3). This enzymatic conversion ultimately regulates calcium ion (Ca2+) mobilization and other intracellular processes. While the precise structural details of GAP1-InsP4 BP activators may vary among different compounds within this chemical class, their shared ability to modulate GAP1 activity makes them crucial tools for researchers studying cellular signaling pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phytic acid solution | 83-86-3 | sc-205806 sc-205806A | 100 ml 500 ml | $151.00 $515.00 | ||
Phytic acid is a naturally occurring compound found in plants, particularly in seeds and grains. It is a strong activator of GAP1-InsP4 BP due to its structural similarity to InsP4. | ||||||
Guanosine 5′-diphosphate sodium salt hydrate (GDP) | 146-91-8 non-salt | sc-507402 | 10 mg | $645.00 | ||
GDP is a nucleotide that can activate GAP1-InsP4 BP by binding to its active site. | ||||||
L-Cysteine | 52-90-4 | sc-286072 sc-286072A sc-286072B sc-286072C sc-286072D | 25 g 100 g 500 g 5 kg 10 kg | $51.00 $112.00 $449.00 $1151.00 $2178.00 | 1 | |
Cysteine, a sulfur-containing amino acid, can also activate GAP1-InsP4 BP by interacting with specific binding sites. | ||||||
L-Proline | 147-85-3 | sc-397196 sc-397196A sc-397196B sc-397196C | 25 g 100 g 1 kg 5 kg | $38.00 $133.00 $208.00 $978.00 | ||
Proline, an amino acid, can affect GAP1-InsP4 BP activity when present in the appropriate context. | ||||||
L-Alanine | 56-41-7 | sc-396825 sc-396825A sc-396825B sc-396825C | 1 g 100 g 500 g 1 kg | $32.00 $102.00 $439.00 $755.00 | ||
Alanine, another amino acid, may play a role in the activation of GAP1-InsP4 BP. | ||||||
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Calcium ions can modulate the activity of GAP1-InsP4 BP, possibly by binding to specific sites on the protein. | ||||||