Fus1 Inhibitors
The class of Fus1 inhibitors comprises a diverse range of chemicals that primarily act through indirect modulation of Fus1 expression and function. These inhibitors target key cellular signaling pathways, disrupting downstream events and subsequently influencing Fus1 activity. One group of Fus1 inhibitors includes p38 MAPK pathway inhibitors such as SB203580 and AS601245. These small molecules dampen the p38 MAPK pathway, leading to altered signaling cascades that impact Fus1 expression and function. The specificity of these inhibitors toward the p38 MAPK pathway provides a controlled approach for investigating Fus1 modulation. Another set of inhibitors, exemplified by SP600125 and SP 800125, targets the JNK signaling pathway. By inhibiting JNK, these compounds indirectly influence Fus1, altering downstream events and providing a specific means to study Fus1 modulation in cellular processes.
The MAPK/ERK pathway is also a key player in Fus1 regulation, and inhibitors like U0126, PD98059, and AZD6244 act by disrupting this pathway. These compounds, through their precise inhibition of MEK1/2, influence Fus1 expression and function, offering controlled tools for studying Fus1 modulation. Additionally, the PI3K/AKT pathway is a significant target for Fus1 modulation, and LY294002, Wortmannin, and PI-103 act as inhibitors of this pathway. Their impact on PI3K/AKT signaling indirectly influences Fus1, providing a specific means for investigating Fus1 modulation in cellular processes. The mTOR pathway is another critical player, and Rapamycin, Torin 1, and AZD6244 inhibit mTOR or its downstream effectors. By disrupting this pathway, these compounds influence Fus1 expression and function, offering controlled tools for studying Fus1 modulation. In summary, the class of Fus1 inhibitors encompasses diverse compounds targeting distinct signaling pathways. These chemicals provide researchers with specific and controlled means to study Fus1 modulation in cellular processes, offering valuable insights into Fus1's role in various biological contexts.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580, a p38 MAPK inhibitor, indirectly modulates Fus1 by dampening the p38 MAPK pathway. This leads to altered downstream signaling, impacting Fus1 expression and function. By inhibiting the p38 MAPK pathway, SB203580 provides a targeted approach to study Fus1 modulation in cellular processes. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, indirectly influences Fus1 through inhibition of the JNK signaling pathway. This alters downstream events, impacting Fus1 expression and function. By targeting the JNK pathway, SP600125 offers a specific means to study Fus1 modulation and its role in cellular processes. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a PI3K inhibitor, indirectly influences Fus1 by inhibiting the PI3K/AKT pathway. This alters downstream signaling, impacting Fus1 expression and function. By targeting the PI3K/AKT pathway, LY294002 offers a specific means to study Fus1 modulation and its role in cellular processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin, an mTOR inhibitor, indirectly modulates Fus1 by inhibiting the mTOR pathway. This disruption affects Fus1 expression and function. By specifically targeting the mTOR pathway, Rapamycin provides a controlled approach for studying Fus1 modulation in cellular processes. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059, a MEK1 inhibitor, indirectly modulates Fus1 by inhibiting the MAPK/ERK pathway. This disruption affects Fus1 expression and function. By specifically targeting the MAPK/ERK pathway, PD98059 provides a controlled approach for studying Fus1 modulation in cellular processes. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin, a PI3K inhibitor, indirectly influences Fus1 by inhibiting the PI3K/AKT pathway. This alters downstream signaling, impacting Fus1 expression and function. By targeting the PI3K/AKT pathway, Wortmannin offers a specific means to study Fus1 modulation and its role in cellular processes. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
Torin 1, a dual mTOR inhibitor, indirectly modulates Fus1 by inhibiting the mTOR pathway. This disruption affects Fus1 expression and function. By specifically targeting the mTOR pathway, Torin 1 provides a controlled approach for studying Fus1 modulation in cellular processes. | ||||||
PI-103 | 371935-74-9 | sc-203193 sc-203193A | 1 mg 5 mg | $32.00 $128.00 | 3 | |
PI-103, a dual PI3K/mTOR inhibitor, indirectly influences Fus1 by inhibiting the PI3K/AKT/mTOR pathway. This alters downstream signaling, impacting Fus1 expression and function. By targeting the PI3K/AKT/mTOR pathway, PI-103 offers a specific means to study Fus1 modulation and its role in cellular processes. | ||||||