Date published: 2025-12-8

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Formin 2 Inhibitors

Formin 2 inhibitors represent a distinctive chemical class of compounds that have attracted scientific interest due to their ability to modulate the activity of the formin 2 protein. Formin 2, also known as FMN2, is a member of the formin family of proteins that play essential roles in the regulation of actin dynamics and cytoskeletal organization. These inhibitors are designed with the intention of interacting with specific domains or regions within the formin 2 protein, thus affecting its function and downstream cellular processes. By engaging with formin 2, these inhibitors have the ability to alter actin filament nucleation, elongation, and bundling, processes that are vital for cellular structure and motility. The significance of formin 2 inhibitors lies in their capacity to shed light on the intricate molecular mechanisms that underlie the functions of formin 2. These inhibitors offer a means to dissect the precise interactions and pathways in which formin 2 participates.

Exploring formin 2 inhibitors entails a comprehensive investigation of the intricate interplay between these compounds and the formin 2 protein. By unraveling the structural and functional details of this interaction, researchers can elucidate the underlying mechanisms that drive formin 2's activity. This knowledge has the ability to unravel novel insights into cellular functions, such as cell motility, adhesion, and morphogenesis, that are intricately linked to the actin cytoskeleton. The study of formin 2 inhibitors contributes to the broader understanding of cytoskeletal dynamics and its implications for cellular processes. While the primary goal of studying formin 2 inhibitors is to decipher their mechanisms of action, these insights have far-reaching implications. By delving into the molecular intricacies of formin 2 inhibition, researchers can gain a deeper understanding of actin cytoskeleton regulation and its impact on various cellular functions. This knowledge can drive innovative research directions and open up avenues for investigating new facets of cell biology, cytoskeletal organization, and cellular motility.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Jasplakinolide

102396-24-7sc-202191
sc-202191A
50 µg
100 µg
$180.00
$299.00
59
(1)

Jasplakinolide is a natural compound that has been used to study Formin 2's role in actin polymerization and dynamics.

SMIFH2

340316-62-3sc-507273
5 mg
$140.00
(0)

SMIFH2 is a small molecule inhibitor that has been reported to target the FH2 domain of Formin 2 and interfere with its actin-nucleating activity.