Compounds like Cytochalasin D, Latrunculin A, and Jasplakinolide directly target the actin cytoskeleton, which is crucial for FNBP3's role in cellular structure and motility. These compounds modulate actin dynamics, thereby affecting FNBP3's function in actin filament organization, cell shape, and movement.
Inhibitors of proteins involved in actin dynamics and signaling, such as Wiskostatin (N-WASP inhibitor), Blebbistatin (myosin II inhibitor), Y-27632 (ROCK inhibitor), ML141 (Cdc42 inhibitor), CK-666 (Arp2/3 complex inhibitor), and NSC23766 (Rac1 inhibitor), provide further insights into the activation of FNBP3's activity. By impacting these key regulatory proteins, these compounds can influence FNBP3's involvement in cytoskeletal reorganization and cell migration. Additionally, the inhibition of signaling pathways like MAPK/ERK by PD98059 and PI3K/Akt by LY294002 could indirectly affect FNBP3's function in cellular responses to various stimuli. Forskolin, by enhancing cAMP levels, might also affect FNBP3-mediated signaling pathways, especially those related to cell motility and adhesion.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, potentially impacting FNBP3's function in actin dynamics and cell morphology regulation. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits N-WASP, affecting actin polymerization and potentially FNBP3's role in cytoskeletal reorganization. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
Inhibits Cdc42 GTPase, potentially affecting FNBP3's role in actin organization and cell morphology. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An MAPK/ERK pathway inhibitor, which could indirectly impact FNBP3's function in cellular responses related to this pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, could influence PI3K/Akt signaling pathways, potentially affecting FNBP3's role in cell survival and migration. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Enhances cAMP levels, potentially influencing FNBP3-mediated signaling pathways, particularly in processes related to cell motility. | ||||||