Date published: 2025-11-24

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Flg Antibodies

Santa Cruz Biotechnology features a diverse variety of Flg Antibodies for multiple research applications. Flg Antibodies are optimized for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Flg protein, also known as filaggrin, plays a crucial role in the formation of the skin barrier and is essential for maintaining skin hydration and integrity. Flg is involved in the aggregation of keratin filaments in the epidermis, contributing to the structural stability of the skin. Dysregulation of Flg expression has been linked to various skin disorders, including atopic dermatitis and ichthyosis, making it a significant focus in dermatological research. Understanding Flg's molecular mechanisms and pathways can provide valuable insights into skin barrier function and development. Research utilizing Flg monoclonal antibodies has revealed important aspects of epidermal differentiation and barrier formation. Ongoing studies of Flg continue to uncover new aspects of skin biology and pathology. Santa Cruz Biotechnology monoclonal antibodies for Flg research support scientists worldwide in advancing our understanding of skin disorders and potential therapeutic approaches.

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Flg Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Flg/FGFR1 Antibody (M2F12)

sc-57132mouse IgG2a κ(h)WB, IP, IF, IHC(P)m, r, h
24
(14)

Flg/FGFR1 Antibody (F-3)

sc-393911mouse IgG2b κ111-122 (h)WB, IP, IF, ELISAm, r, h
2
(5)

Flg/FGFR1 Antibody (M5G10)

sc-57133mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h

new

(2)

Flg CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Flg/FGFR1 CRISPR/Cas9 KO Plasmid (h)

sc-418289hGene KnockoutGFP0
(0)

Flg/FGFR1 HDR Plasmid (h)

sc-418289-HDRhHomology Directed RepairPuromycin0
(0)

Flg/FGFR1 Double Nickase Plasmid (h)

sc-418289-NIChGene KnockoutPuromycin0
(0)

Flg/FGFR1 Double Nickase Plasmid (h2)

sc-418289-NIC-2hGene KnockoutPuromycin0
(0)

Flg/FGFR1 CRISPR/Cas9 KO Plasmid (m)

sc-420341mGene KnockoutGFP0
(0)

Flg/FGFR1 HDR Plasmid (m)

sc-420341-HDRmHomology Directed RepairPuromycin0
(0)

Flg/FGFR1 Double Nickase Plasmid (m)

sc-420341-NICmGene KnockoutPuromycin0
(0)

Flg/FGFR1 Double Nickase Plasmid (m2)

sc-420341-NIC-2mGene KnockoutPuromycin0
(0)

Flg CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Flg/FGFR1 CRISPR Activation Plasmid (h)

sc-418289-ACThGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 CRISPR Activation Plasmid (h2)

sc-418289-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 Lentiviral Activation Particles (h)

sc-418289-LAChGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 Lentiviral Activation Particles (h2)

sc-418289-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 CRISPR Activation Plasmid (m)

sc-420341-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 CRISPR Activation Plasmid (m2)

sc-420341-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 Lentiviral Activation Particles (m)

sc-420341-LACmGene ActivationPuro, Blast, Hygro0
(0)

Flg/FGFR1 Lentiviral Activation Particles (m2)

sc-420341-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Flg siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Flg/FGFR1 siRNA (h)

sc-29316hGene SilencingN/A
10
(0)

Flg/FGFR1 shRNA Plasmid (h)

sc-29316-SHhGene SilencingPuromycin
10
(0)

Flg/FGFR1 shRNA (h) Lentiviral Particles

sc-29316-VhGene SilencingPuromycin
10
(0)

Flg/FGFR1 siRNA (m)

sc-29317mGene SilencingN/A
10
(0)

Flg/FGFR1 shRNA Plasmid (m)

sc-29317-SHmGene SilencingPuromycin
10
(0)

Flg/FGFR1 shRNA (m) Lentiviral Particles

sc-29317-VmGene SilencingPuromycin
10
(0)

Flg/FGFR1 siRNA (r)

sc-61890rGene SilencingN/A
2
(0)

Flg/FGFR1 shRNA Plasmid (r)

sc-61890-SHrGene SilencingPuromycin
2
(0)

Flg/FGFR1 shRNA (r) Lentiviral Particles

sc-61890-VrGene SilencingPuromycin
2
(0)