FKBP8 Inhibitors
FKBP8 inhibitors belong to a specific chemical class of compounds designed to selectively inhibit the activity of FKBP8 (also known as FKBP38), a member of the FK506-binding protein (FKBP) family. FKBP8 is involved in various cellular processes, including apoptosis and calcium homeostasis. Inhibiting FKBP8 activity is of interest to researchers as it may provide valuable insights into its functional roles and cellular pathways. These inhibitors are small molecules or compounds that are designed to interact with FKBP8, interfering with its enzymatic or protein-binding function. The goal of developing FKBP8 inhibitors is to better understand the regulatory roles of FKBP8 in cellular processes and its implications in various biological functions.
Medicinal chemists utilize computational and structural biology techniques to design and optimize FKBP8 inhibitors, aiming for high selectivity and potency to specifically target FKBP8 while minimizing interactions with other FKBP family members. Research on FKBP8 inhibitors is ongoing, and it continues to contribute to our understanding of the role of FKBP8 in cellular biology.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PK 11195 | 85532-75-8 | sc-203199 sc-203199A | 10 mg 50 mg | $86.00 $315.00 | ||
A well-known compound that has been reported to inhibit FKBP8 in certain cellular contexts. | ||||||
FK-506 | 104987-11-3 | sc-24649 sc-24649A | 5 mg 10 mg | $76.00 $148.00 | 9 | |
A widely used immunosuppressive drug that can interact with FKBP family members, including FKBP8. | ||||||
Everolimus | 159351-69-6 | sc-218452 sc-218452A | 5 mg 50 mg | $128.00 $638.00 | 7 | |
An inhibitor used in cancer therapy, which can also affect FKBP8 due to its similarity to FK506. | ||||||
3′-Azido-3′-deoxythymidine | 30516-87-1 | sc-203319 | 10 mg | $60.00 | 2 | |
A nucleoside analog used in antiviral therapies, which has been shown to inhibit FKBP8 in certain experimental conditions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
A natural product that forms a complex with FKBP family proteins, including FKBP8. | ||||||
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressive drug that can interact with FKBP8, among other FKBP family members. | ||||||