Fibulin-1 Inhibitors
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Tanshinone IIA | 568-72-9 | sc-200932 sc-200932A | 5 mg 25 mg | $88.00 $316.00 | 22 | |
Tanshinone IIA is a natural compound found in Salvia miltiorrhiza. It has been reported to inhibit the TGF-β/Smad signaling pathway, potentially impacting cellular processes associated with Fibulin-1 modulation. | ||||||
Halofuginone | 55837-20-2 | sc-507290 | 100 mg | $1775.00 | ||
Halofuginone is a synthetic derivative of febrifugine and inhibits TGF-β/Smad signaling. Its interference with this pathway suggests a potential indirect inhibitory effect on Fibulin-1, as Fibulin-1 is known to be regulated by TGF-β. | ||||||
BIBF1120 | 656247-17-5 | sc-364433 sc-364433A | 5 mg 10 mg | $184.00 $321.00 | 2 | |
BIBF1120 is a tyrosine kinase inhibitor targeting receptors involved in fibrotic processes. By inhibiting these receptors, Nintedanib can potentially modulate signaling cascades related to Fibulin-1, offering a route for indirect inhibition. | ||||||
TGF-β RI Kinase Inhibitor VIII | 356559-20-1 | sc-203295 | 2 mg | $100.00 | 2 | |
TGF-β RI Kinase Inhibitor VIII (SB525334) is a selective inhibitor of the TGF-β receptor I (ALK5). By targeting this receptor, SB525334 disrupts TGF-β signaling pathways, potentially influencing cellular processes associated with Fibulin-1 activity. | ||||||
LY 364947 | 396129-53-6 | sc-203122 sc-203122A | 5 mg 10 mg | $107.00 $156.00 | 4 | |
LY364947 is a selective inhibitor of the TGF-β receptor, targeting the TGF-β signaling pathway. Inhibition of the TGF-β receptor by LY364947 may impact cellular processes linked to Fibulin-1 modulation, suggesting a potential indirect inhibitory effect. | ||||||
A 83-01 | 909910-43-6 | sc-203791 sc-203791A | 10 mg 50 mg | $202.00 $811.00 | 16 | |
A83-01 is an inhibitor of the TGF-β type I receptor (ALK5). By targeting this receptor, A83-01 disrupts TGF-β signaling pathways, potentially influencing cellular processes associated with Fibulin-1 activity. | ||||||
Pirfenidone | 53179-13-8 | sc-203663 sc-203663A | 10 mg 50 mg | $102.00 $416.00 | 6 | |
Pirfenidone is an anti-fibrotic agent that modulates TGF-β signaling and inhibits fibroblast proliferation. Its impact on TGF-β pathways suggests a potential indirect inhibitory effect on Fibulin-1, a protein implicated in fibrotic processes. | ||||||
LY2109761 | 700874-71-1 | sc-396262 sc-396262A | 1 mg 5 mg | $89.00 $275.00 | 9 | |
LY2109761 is a TGF-β receptor type I/II dual inhibitor. By targeting both receptors, LY2109761 disrupts TGF-β signaling pathways, potentially influencing cellular processes associated with Fibulin-1 activity. | ||||||
ALK5 Inhibitor II | 446859-33-2 | sc-221234 sc-221234A sc-221234B sc-221234C sc-221234D sc-221234E sc-221234F | 1 mg 5 mg 10 mg 50 mg 100 mg 500 mg 1 g | $77.00 $153.00 $219.00 $663.00 $1248.00 $4382.00 $7850.00 | 8 | |
ALK5 Inhibitor II (RepSox) is a small molecule inhibitor of TGF-β type I receptor ALK5. Its inhibition of ALK5 suggests a potential indirect inhibitory effect on Fibulin-1, as Fibulin-1 is known to be regulated by TGF-β signaling. | ||||||
GW788388 | 452342-67-5 | sc-363544 sc-363544A | 5 mg 25 mg | $95.00 $384.00 | ||
GW788388 is a selective inhibitor of TGF-β type I receptor (ALK5). By inhibiting ALK5, GW788388 disrupts TGF-β signaling pathways, potentially influencing cellular processes associated with Fibulin-1 activity. | ||||||