FHOD3 Activators
The FHOD3 Activators chemical class includes compounds that indirectly influence the activity of FHOD3, mainly through their effects on the actin cytoskeleton and related cellular processes. These activators primarily function by altering the dynamics of actin polymerization, muscle contraction, and cellular motility, which are key areas of FHOD3's involvement. Compounds such as Phalloidin, Jasplakinolide, and Latrunculin B directly target actin filaments, either stabilizing or disrupting them. These alterations in actin dynamics can have downstream effects on FHOD3, which plays a critical role in organizing and maintaining the actin cytoskeleton. For example, stabilization of actin filaments by Phalloidin could enhance FHOD3's activity in actin assembly and organization, while disruption of these filaments by Latrunculin B might require compensatory activity from FHOD3.
Other compounds in this class, like Y-27632, Blebbistatin, and ML-7, affect muscle contraction and cell motility processes. By modulating the activity of proteins involved in these processes, such as ROCK, myosin II, and myosin light chain kinase, these compounds indirectly influence the role of FHOD3 in these cellular functions. For instance, inhibition of myosin II by Blebbistatin may increase the dependence on FHOD3 for maintaining muscle contraction dynamics.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Binds to and stabilizes actin filaments, potentially enhancing FHOD3 activity in actin cytoskeleton organization. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
A cyclic peptide that stabilizes actin filaments, potentially affecting FHOD3 function in actin dynamics. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, known to affect actin cytoskeleton dynamics, potentially modulating FHOD3 activity in cell motility. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits myosin II, affecting muscle contraction and potentially enhancing FHOD3's role in this process. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $321.00 $1040.00 | 5 | |
An Arp2/3 complex inhibitor, affecting actin polymerization, and potentially influencing FHOD3 activity in actin cytoskeleton organization. | ||||||
Latrunculin B | 76343-94-7 | sc-203318 | 1 mg | $240.00 | 29 | |
Binds to actin monomers, disrupting actin polymerization and potentially affecting FHOD3's function in actin dynamics. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Disrupts actin filament polymerization, potentially influencing FHOD3 activity in cellular processes involving actin. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, leading to increased cAMP levels and potentially affecting pathways involving FHOD3 in muscle cells. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
A known stimulant that can influence calcium release in muscle cells, potentially affecting FHOD3 activity. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule polymerization, potentially affecting cellular processes that involve FHOD3. | ||||||