FGFR-3 Inhibitors
Santa Cruz Biotechnology now offers a broad range of FGFR-3 Inhibitors. Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. FGFR-3 Inhibitors offered by Santa Cruz inhibit FGFR-3 and, in some cases, other cell proliferation and growth factor related proteins. View detailed FGFR-3 Inhibitor specifications, including FGFR-3 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AZD4547 | 1035270-39-3 | sc-364421 sc-364421A | 5 mg 10 mg | $198.00 $309.00 | 6 | |
AZD4547 is a selective FGFR-3 inhibitor that competes with ATP for binding to the FGFR-3 kinase domain. By blocking FGFR-3 phosphorylation, it inhibits downstream signaling pathways involved in cancer growth. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $47.00 $143.00 $680.00 | 16 | |
PD173074 (CAS 219580-11-7) is a compound known for its ability to inhibit FGFR-3, a receptor involved in cellular signaling. | ||||||
Erdafitinib | 1346242-81-6 | sc-507388 | 10 mg | $138.00 | ||
Erdafitinib is a tyrosine kinase inhibitor that selectively targets FGFR-3. It inhibits FGFR-3 by competitively binding to the ATP-binding pocket, thereby blocking downstream signaling pathways involved in cell proliferation. | ||||||
Masitinib | 790299-79-5 | sc-211777 | 10 mg | $184.00 | ||
Masitinib (CAS 790299-79-5) is a compound that functions as an inhibitor of FGFR-3, a receptor involved in cellular signaling. | ||||||
BGJ398 | 872511-34-7 | sc-364430 sc-364430A sc-364430B sc-364430C | 5 mg 10 mg 50 mg 100 mg | $216.00 $252.00 $594.00 $1009.00 | 4 | |
BGJ398 is a potent and selective FGFR inhibitor that binds to the ATP pocket of FGFR-3. By inhibiting FGFR-3 phosphorylation, it disrupts downstream signaling, impeding tumor growth and angiogenesis. | ||||||
BIBF1120 | 656247-17-5 | sc-364433 sc-364433A | 5 mg 10 mg | $184.00 $321.00 | 2 | |
BIBF1120 (CAS 656247-17-5) functions as an FGFR-3 inhibitor by interacting with the receptor and disrupting its signaling pathways. This interference with FGFR-3 activity can have various biological effects. | ||||||
PF 477736 | 952021-60-2 | sc-362781 sc-362781A | 5 mg 25 mg | $115.00 $431.00 | ||
PF 477736 (CAS 952021-60-2) is a chemical compound that acts as an inhibitor of FGFR-3, a receptor involved in cellular signaling processes. Its specific mechanism of inhibiting FGFR-3 contributes to its biological effects. | ||||||
Debio-1347 | 1265229-25-1 | sc-507386 | 10 mg | $324.00 | ||
Debio1347 is al FGFR-3 inhibitor that hinders the kinase activity of FGFR-3. It works by blocking the autophosphorylation of FGFR-3 and downstream signaling pathways, thereby inhibiting tumor growth. | ||||||
Dovitinib, Free Base | 405169-16-6 | sc-396771 sc-396771A | 10 mg 25 mg | $170.00 $350.00 | ||
Dovitinib, Free Base (CAS 405169-16-6) is a chemical compound known for its role as an inhibitor of FGFR-3, a receptor involved in cellular signaling. Its mechanism of action disrupts FGFR-3 signaling pathways. | ||||||
Debio 0932 | 1061318-81-7 | sc-507516 | 10 mg | $280.00 | ||
Debio 0932 is an active FGFR inhibitor. It selectively targets FGFR-3 by binding to the ATP pocket, inhibiting FGFR-3 autophosphorylation and downstream signaling, ultimately suppressing tumor growth. | ||||||