Molecular structure of Debio 0932, CAS Number: 1061318-81-7
Debio 0932 (CAS 1061318-81-7)
Alternate Names:
CUDC-305
CAS Number:
1061318-81-7
Molecular Weight:
442.58
Molecular Formula:
C22H30N6O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Debio 0932 (CAS 1061318-81-7) References
- Debio 0932, a new oral Hsp90 inhibitor, alleviates psoriasis in a xenograft transplantation model. | Stenderup, K., et al. 2014. Acta Derm Venereol. 94: 672-6. PMID: 24604074
- Debio-0932, a second generation oral Hsp90 inhibitor, induces apoptosis in MCF-7 and MDA-MB-231 cell lines. | Özgür, A., et al. 2021. Mol Biol Rep. 48: 3439-3449. PMID: 33999319
- Evolution of kinase polypharmacology across HSP90 drug discovery. | Antolin, AA., et al. 2021. Cell Chem Biol. 28: 1433-1445.e3. PMID: 34077750
- Heat shock proteins and cancer: The FoxM1 connection. | Alimardan, Z., et al. 2023. Biochem Pharmacol. 211: 115505. PMID: 36931349
- Machine learning approach to screen new diagnostic features of adamantinomatous craniopharyngioma and explore personalised treatment strategies. | Wu, J., et al. 2023. Transl Pediatr. 12: 947-966. PMID: 37305719
- Pan-cancer analysis of SERPINE family genes as biomarkers of cancer prognosis and response to therapy. | Liu, Y., et al. 2023. Front Mol Biosci. 10: 1277508. PMID: 38274096
- Heat shock protein 90 inhibition attenuates inflammation in models of atopic dermatitis: a novel mechanism of action. | Ben Abdallah, H., et al. 2023. Front Immunol. 14: 1289788. PMID: 38274815
- Heat shock protein 90: biological functions, diseases, and therapeutic targets. | Wei, H., et al. 2024. MedComm (2020). 5: e470. PMID: 38283176
- Combination of navitoclax (Bcl-2 and Bcl-xL inhibitor) and Debio-0932 (Hsp90 inhibitor) suppresses the viability of prostate cancer cells via induction of apoptotic signaling pathway. | Asdemir, A. and Özgür, A. 2024. Med Oncol. 41: 83. PMID: 38436810
- HSPA4 upregulation induces immune evasion via ALKBH5/CD58 axis in gastric cancer. | Suo, D., et al. 2024. J Exp Clin Cancer Res. 43: 106. PMID: 38589927
Inhibitor of:
FGFR-3, FKBP52, HSP 90α, SGT1, TID-1L, and XAP2.Activator of:
Cdc37, CyPB, and HSP 78.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Debio 0932, 10 mg | sc-507516 | 10 mg | $280.00 |