Date published: 2026-1-25

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FGF-3 Inhibitors

FGF-3 inhibitors represent a category of chemical compounds designed to selectively modulate the activity of Fibroblast Growth Factor 3 (FGF-3). FGF-3 is a member of the fibroblast growth factor family, a group of signaling proteins that play essential roles in various cellular processes, including cell proliferation, differentiation, and tissue development. The inhibition of FGF-3 is of particular interest in understanding the intricate regulatory mechanisms governing cellular growth and differentiation. The chemical structures of FGF-3 inhibitors are meticulously crafted to interact with specific binding sites on the FGF-3 protein, thereby impeding its normal function within the cellular signaling cascade. The development and study of FGF-3 inhibitors aim to unravel the biological significance of FGF-3 in cellular processes. By selectively inhibiting FGF-3, researchers can investigate the downstream effects on cell signaling pathways and gain insights into the broader implications for tissue development and homeostasis. These inhibitors may function through various mechanisms, such as competitive binding to the FGF-3 receptor or interfering with the interaction between FGF-3 and its downstream signaling partners. Exploring FGF-3 inhibitors contributes to the foundational knowledge of molecular and cellular biology, offering a platform for the investigation of intricate signaling networks and potential avenues for further research into the regulation of cellular growth and development.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Suramin sodium

129-46-4sc-507209
sc-507209F
sc-507209A
sc-507209B
sc-507209C
sc-507209D
sc-507209E
50 mg
100 mg
250 mg
1 g
10 g
25 g
50 g
$152.00
$214.00
$728.00
$2601.00
$10965.00
$21838.00
$41096.00
5
(1)

This compound has been shown to inhibit the binding of FGFs to their receptors, potentially influencing FGF-3 activity indirectly.

PD173074

219580-11-7sc-202610
sc-202610A
sc-202610B
1 mg
5 mg
50 mg
$47.00
$143.00
$680.00
16
(1)

This is a selective FGFR inhibitor. Changes in FGFR activity could indirectly influence FGF-3.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

An inhibitor of PI3K, a downstream effector in the FGF signaling pathway. Changes in PI3K activity could indirectly influence FGF-3.