FcRn Antibodies

Santa Cruz Biotechnology features a diverse variety of FcRn monoclonal antibodies for various research applications. Validated applications include western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). The neonatal Fc receptor (FcRn) plays a crucial role in the regulation of immunoglobulin G (IgG) and albumin levels in the bloodstream, influencing both immune response and therapeutic antibody half-life. FcRn binds to IgG and protects it from degradation, extending circulation time and enhancing efficacy in therapeutic applications. Understanding FcRn function is essential for developing strategies to improve antibody-based therapies and for studying immune system dynamics. Researchers working with FcRn can explore its role in maintaining IgG homeostasis and investigate potential therapeutic interventions. Advanced detection methods using conjugated secondary antibodies, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), enable precise visualization and quantification of FcRn expression patterns. Santa Cruz Biotechnology monoclonal antibodies support cutting-edge research that advances our understanding of immune system regulation and therapeutic development.