FBXO15 Activators
Regarding the chemical class of (FBXO15) Activators, these are compounds that can influence the activity of the FBXO15 protein, albeit indirectly. They primarily work by blocking the proteasome, the complex responsible for degrading proteins marked with ubiquitin. By inhibiting this complex, these compounds can affect the proteins involved in the ubiquitin-proteasome pathway, including FBXO15. These compounds, such as MG132, Lactacystin, and Bortezomib, are often used in research to study the ubiquitin-proteasome pathway and related proteins.
The functional mechanisms of these compounds are centered around their ability to inhibit the proteasome. MG132 is a cell-permeable proteasome inhibitor that can block the degradation of proteins marked by E3 ubiquitin ligases, such as FBXO15. Lactacystin is another potent and specific proteasome inhibitor that can influence the activity of proteins involved in this pathway. Bortezomib also functions as a proteasome inhibitor. These compounds offer a way to study the indirect modulation of FBXO15 activity through ubiquitin-proteasome pathway inhibition.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
An activator of SIRT1, Resveratrol indirectly modulates the activities of various proteins including FBXO15. SIRT1, a NAD-dependent deacetylase, is known to interact with a host of proteins in the cell, influencing many cellular processes. Through the activation of SIRT1, Resveratrol might contribute to the modification and possible activation of FBXO15. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a major active polyphenol of green tea that has been demonstrated to influence many cellular pathways. One of these pathways includes the PI3K/AKT pathway, which has downstream effects on various proteins, including those involved in ubiquitination processes. Hence, it is possible that EGCG could indirectly influence the activity of FBXO15. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate the activity of numerous cellular pathways including the PI3K/AKT pathway. This could indirectly influence the activity of FBXO15 as it is involved in the ubiquitination process, a mechanism which is known to be modulated by the PI3K/AKT pathway. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can influence the PI3K/AKT pathway, which has downstream effects on numerous proteins. By modulating these pathways, Genistein could indirectly influence the activity of FBXO15. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Known as a potent antioxidant, Quercetin could influence the activity of several cellular pathways, including the PI3K/AKT pathway, which is known to have downstream effects on the ubiquitination process where FBXO15 is involved. | ||||||