Date published: 2026-5-14

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Fatso Inhibitors

The chemical class known as Fatso Inhibitors encompasses a diverse array of molecules and compounds that have been developed and investigated for their ability to modulate the activity of the fat mass and obesity-associated protein, commonly referred to as "Fatso" (Fto). Fto is an enzyme that plays a role in RNA demethylation, and it has garnered significant attention for its involvement in the regulation of body weight, energy balance, and metabolic processes. Fatso Inhibitors are meticulously designed to interact with Fto or related pathways, aiming to influence its enzymatic activity and, consequently, its impact on RNA methylation. By targeting Fto, these inhibitors provide a means to explore and manipulate the intricate mechanisms underlying RNA modifications and their implications in physiological contexts.

The study of Fatso Inhibitors contributes to advancing our understanding of molecular processes associated with metabolism and energy regulation, shedding light on the complex interplay of cellular components that govern fundamental biological functions. Ongoing research endeavors seek to elucidate the mechanisms of action and broader effects attributed to Fatso Inhibitors, thereby enhancing our insights into the intricate web of molecular interactions within the realm of cellular metabolism.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

D-α-Hydroxyglutaric acid disodium salt

103404-90-6sc-227739
sc-227739A
sc-227739B
25 mg
250 mg
1 g
$122.00
$820.00
$2652.00
2
(1)

An oncometabolite that has been shown to inhibit FTO activity by competing with its substrate, leading to increased RNA methylation.

Meclofenamic Acid

644-62-2sc-211780
5 mg
$402.00
(0)

This nonsteroidal anti-inflammatory drug (NSAID) has been reported to inhibit FTO activity and alter RNA methylation levels.

Rhein

478-43-3sc-205837
sc-205837A
100 mg
500 mg
$267.00
$333.00
2
(1)

A natural compound found in certain plants, rhein has been explored for its inhibitory effects on FTO activity.