Fascin 2 Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Thymoquinone | 490-91-5 | sc-215986 sc-215986A | 1 g 5 g | $46.00 $130.00 | 21 | |
Derived from the seeds of Nigella sativa (black seed), thymoquinone is known for its anti-inflammatory and anti-cancer properties. Regarding Fascin, thymoquinone has been shown to inhibit its expression and, as a result, suppress cell invasion and migration in certain cancer cell lines. The exact mechanism by which thymoquinone inhibits Fascin is still under investigation, but it's believed to act through multiple cellular pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A polyphenolic compound from turmeric, curcumin possesses anti-inflammatory, antioxidant, and anti-cancer properties. It has been found to downregulate Fascin expression in certain cancer cells, leading to the suppression of cell invasion and metastasis. Curcumin's effect on Fascin might be due to its ability to modulate various signaling pathways, including the Wnt/β-catenin pathway. | ||||||
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
An omega-3 fatty acid, DHA has anti-inflammatory and anti-cancer effects. Studies have indicated that DHA can suppress Fascin expression in certain cancer cell lines. The suppression of Fascin by DHA could be linked to its modulation of the NF-κB signaling pathway. | ||||||
Tolfenamic Acid | 13710-19-5 | sc-204918 sc-204918A | 5 g 25 g | $69.00 $312.00 | ||
A non-steroidal anti-inflammatory drug (NSAID), tolfenamic acid has been shown to suppress Fascin expression and inhibit cancer cell invasion. Its mechanism might involve the suppression of the SP1 transcription factor, which regulates Fascin expression. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $103.00 $210.00 $6132.00 | 2 | |
Derived from the rhubarb plant, emodin has anti-cancer properties. It inhibits Fascin-mediated filopodia formation, potentially through its effects on the PI3K/AKT pathway. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $97.00 $212.00 $500.00 | 11 | |
A natural flavonoid, kaempferol has been found to suppress Fascin expression in certain cancer cell lines. The exact mechanism remains to be elucidated, but kaempferol's broad range of targets, including the modulation of various kinase activities, could contribute to its effects on Fascin. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
A soy isoflavone, genistein has anti-cancer properties. It suppresses Fascin-mediated cell migration and invasion. Genistein might act by inhibiting tyrosine kinases and modulating the estrogen receptor pathway, which can have downstream effects on Fascin expression. | ||||||