Date published: 2026-5-16

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FAM48B2 Inhibitors

The chemical class of FAM48B2 Inhibitors encompasses a range of compounds that can potentially inhibit the activity of the FAM48B2 protein, primarily by targeting glycogen synthase kinase 3 (GSK-3). FAM48B2 may be involved in cellular processes regulated by GSK-3-mediated signaling pathways, including cell proliferation, differentiation, and survival. Inhibition of GSK-3 by these compounds disrupts downstream signaling events, potentially leading to the inhibition of FAM48B2 function.

GSK-3 inhibitors such as SB216763, LY2090314, CHIR99021, TDZD-8, BIO, Tideglusib, SB415286, TWS119, AR-A014418, CHIR98014, AZD1080, and TCS 359 selectively target GSK-3, preventing its activity and interfering with downstream signaling cascades that involve FAM48B2. By disrupting these pathways, GSK-3 inhibitors can indirectly inhibit FAM48B2 function, highlighting the significance of GSK-3-mediated signaling in regulating cellular processes involving FAM48B2. These inhibitors provide valuable tools for investigating the role of FAM48B2 in cellular physiology and may have implications in various biological and pathological contexts.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SB-216763

280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$71.00
$202.00
18
(1)

SB216763 is a selective inhibitor of glycogen synthase kinase 3 (GSK-3), an enzyme involved in various cellular processes including cell signaling, metabolism, and gene expression. FAM48B2 may be regulated by GSK-3-mediated pathways, and inhibition of GSK-3 by SB216763 can potentially disrupt these pathways, leading to inhibition of FAM48B2 function.

LY2090314

603288-22-8sc-507359
5 mg
$175.00
(0)

LY2090314 is a potent inhibitor of glycogen synthase kinase 3 (GSK-3), which regulates multiple cellular processes including cell proliferation and survival. FAM48B2 may be modulated by GSK-3-mediated signaling pathways, and inhibition of GSK-3 by LY2090314 can interfere with these pathways, potentially inhibiting FAM48B2 activity.

GSK-3 Inhibitor XVI

252917-06-9sc-221691
sc-221691A
5 mg
25 mg
$180.00
$610.00
4
(1)

CHIR99021 is a highly selective inhibitor of glycogen synthase kinase 3 (GSK-3), an enzyme involved in the regulation of various cellular processes including cell proliferation and differentiation. FAM48B2 may be influenced by GSK-3-mediated signaling cascades, and inhibition of GSK-3 by CHIR99021 can potentially disrupt these pathways, leading to inhibition of FAM48B2 function.

GSK-3 Inhibitor IX

667463-62-9sc-202634
sc-202634A
sc-202634B
1 mg
10 mg
50 mg
$58.00
$188.00
$884.00
10
(1)

BIO is a potent and selective inhibitor of glycogen synthase kinase 3 (GSK-3), a key regulator of various cellular processes including cell proliferation and differentiation. FAM48B2 may be modulated by GSK-3-mediated signaling pathways, and inhibition of GSK-3 by BIO can disrupt these pathways, potentially inhibiting FAM48B2 function.

Tideglusib

865854-05-3sc-507358
10 mg
$77.00
(0)

Tideglusib is an irreversible inhibitor of glycogen synthase kinase 3 (GSK-3), an enzyme involved in the regulation of multiple cellular processes including cell proliferation and apoptosis. FAM48B2 may be influenced by GSK-3-mediated signaling pathways, and inhibition of GSK-3 by Tideglusib can potentially disrupt these pathways, leading to inhibition of FAM48B2 activity.

GSK-3β Inhibitor VIII

487021-52-3sc-202636
sc-202636A
5 mg
10 mg
$134.00
$150.00
5
(1)

AR-A014418 is a selective inhibitor of glycogen synthase kinase 3 (GSK-3), which plays a crucial role in the regulation of various cellular processes including cell proliferation and survival. FAM48B2 may be influenced by GSK-3-mediated signaling pathways, and inhibition of GSK-3 by AR-A014418 can potentially disrupt these pathways, leading to inhibition of FAM48B2 activity.

AZD1080

612487-72-6sc-503187
2.5 mg
$280.00
(0)

AZD1080 is a selective inhibitor of glycogen synthase kinase 3 (GSK-3), which regulates various cellular processes including cell cycle progression and apoptosis. FAM48B2 may be regulated by GSK-3-mediated pathways, and inhibition of GSK-3 by AZD1080 can potentially interfere with these pathways, leading to inhibition of FAM48B2 function.