FAM43A, also known as Family with Sequence Similarity 43 Member A, is a protein encoded by the FAM43A gene in humans.The FAM43A gene is conserved in many organisms, suggesting its biological importance, but the precise roles it plays in cellular processes remain largely unknown.The FAM43A protein is reported to be ubiquitously expressed in various tissues, indicating that it may perform broad biological functions. Its name derives from its inclusion in a family of proteins that share sequence similarity, but the overall functions of the FAM43 family have not been fully defined.
Bioinformatic analyses show that the FAM43A protein contains a domain of unknown function (DUF1394). Proteins with DUFs are often targets for functional characterization since they represent potential new areas for exploration in cell biology.While the exact roles of FAM43A in human health and disease are not yet established, studies suggest potential links to cancer. For instance, a few reports suggest that the FAM43A gene may be differentially expressed in certain cancer types, which could imply a role in tumorigenesis or cancer progression. However, these findings require further validation and investigation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences cell differentiation and proliferation, potentially affecting gene expression through retinoic acid receptors. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Vitamin D3, via its hormonal form, may affect gene expression through the vitamin D receptor, which could include genes like FAM43A. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate is a histone deacetylase inhibitor that can lead to a more accessible chromatin state and potentially enhance gene expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inducing ER stress, tunicamycin activates the unfolded protein response, which may influence the expression of genes involved in dealing with misfolded proteins. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Like tunicamycin, thapsigargin induces ER stress and the unfolded protein response, potentially affecting gene expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
By inhibiting ribonucleotide reductase, hydroxyurea can induce replication stress, potentially affecting the expression of stress response genes. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
As a synthetic glucocorticoid, dexamethasone can regulate genes involved in inflammation and immune response through the glucocorticoid receptor. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG has been shown to modulate various signaling pathways and might influence gene expression related to antioxidant defense mechanisms. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin affects multiple signaling pathways and could modulate gene expression profiles due to its anti-inflammatory and antioxidant properties. | ||||||