FAM178A Inhibitors
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cisplatin | 15663-27-1 | sc-200896 sc-200896A | 100 mg 500 mg | $138.00 $380.00 | 101 | |
Cisplatin is a platinum-based chemotherapy compound that can inhibit FAM178A by forming covalent adducts with DNA, leading to DNA damage and interfering with the DNA repair process. | ||||||
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Aphidicolin is a DNA polymerase inhibitor that can inhibit FAM178A indirectly by blocking DNA replication, preventing the formation of replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) that require the recruitment of the SMC5-SMC6 complex. | ||||||
VE 821 | 1232410-49-9 | sc-475878 | 10 mg | $360.00 | ||
VE 821 is a selective inhibitor of the ATR kinase, which is involved in the DNA damage response pathway. By inhibiting ATR, VE 821 can indirectly inhibit FAM178A by disrupting the postreplication repair of UV-damaged DNA and impairing the recruitment of the SMC5-SMC6 complex to DNA lesions. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
ATM Kinase Inhibitor is a selective inhibitor of the ATM kinase, another key player in the DNA damage response pathway. Inhibition of ATM can disrupt the DNA repair process and hinder the recruitment of the SMC5-SMC6 complex, indirectly inhibiting FAM178A. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
Camptothecin is a topoisomerase I inhibitor that can induce DNA damage and interfere with DNA repair mechanisms. By inhibiting topoisomerase I, camptothecin can indirectly inhibit FAM178A by disrupting the repair of DNA lesions that require the recruitment of the SMC5-SMC6 complex. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Olaparib is a poly(ADP-ribose) polymerase (PARP) inhibitor that can impair DNA repair mechanisms, particularly the base excision repair pathway. By inhibiting PARP, olaparib can indirectly inhibit FAM178A by interfering with the repair of DNA lesions that require the recruitment of the SMC5-SMC6 complex. | ||||||
NU 7441 | 503468-95-9 | sc-208107 | 5 mg | $357.00 | 10 | |
NU 7441 is a selective inhibitor of DNA-dependent protein kinase (DNA-PK), a key enzyme involved in the non-homologous end joining (NHEJ) pathway of DNA repair. By inhibiting DNA-PK, NU 7441 can indirectly inhibit FAM178A by disrupting the repair of DNA double-strand breaks that require the recruitment of the SMC5-SMC6 complex. | ||||||
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $62.00 $87.00 | 4 | |
Tozasertib is a potent inhibitor of Aurora kinases, which are involved in cell cycle regulation and DNA repair processes. Inhibition of Aurora kinases can indirectly inhibit FAM178A by disrupting cell cycle progression and impairing the recruitment of the SMC5-SMC6 complex to DNA lesions. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Suberoylanilide Hydroxamic Acid is a histone deacetylase (HDAC) inhibitor that can modulate chromatin structure and gene expression. By inhibiting HDACs, Suberoylanilide Hydroxamic Acid can indirectly inhibit FAM178A by affecting the chromatin environment and potentially impairing the recruitment of the SMC5-SMC6 complex to DNA lesions. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
Bortezomib is a reversible inhibitor of the 26S proteasome, which is involved in protein degradation and regulation. By inhibiting the proteasome, bortezomib can indirectly inhibit FAM178A by affecting protein turnover and potentially disrupting the recruitment of the SMC5-SMC6 complex to DNA lesions. | ||||||