FAM171A1 Activators
FAM171A1 activators are chemical compounds that indirectly promote the functional activity of FAM171A1 through modulation of various signaling pathways. For instance, Phorbol 12-myristate 13-acetate (PMA) and Ionomycin are potent activators of protein kinase C (PKC) and calcium-dependent kinases, respectively, both of which may phosphorylate FAM171A1, thereby enhancing its activity in cellular signaling. Similarly, Forskolin and Zaprinast elevate intracellular cAMP, subsequently activating PKA, which is another kinase that can target FAM171A1 for phosphorylation. In this context, phosphorylation serves as a critical regulatory mechanism by which the activity of FAM171A1 is increased. Sphingosine-1-phosphate, by binding to its receptors, initiates a cascade of events culminating in kinase activation, which may include those responsible for FAM171A1 phosphorylation. Epigallocatechin gallate (EGCG) exerts its effects by inhibiting competing protein kinases, thereby potentially enhancing the phosphorylation status of FAM171A1.
A23187 (Calcimycin) and Anisomycin both modulate intracellular calcium levels and stress-activated protein kinases, pathways that can lead to phosphorylation and subsequent activation of FAM171A1. The action of Olomoucine, as a cyclin-dependent kinase inhibitor, may indirectly result in the enhanced phosphorylation and activation of FAM171A1 by altering the cellular phosphorylation landscape.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
A diacylglycerol (DAG) analog that activates protein kinase C (PKC). PKC has been implicated in the phosphorylation of FAM171A1, thereby enhancing its functional activity within cellular signaling pathways. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
A calcium ionophore that raises intracellular calcium levels, indirectly activating calcium-dependent protein kinases which could phosphorylate FAM171A1, thus enhancing its activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
A lipid signaling molecule that activates sphingosine-1-phosphate receptors, leading to downstream signaling events that may include the activation of kinases capable of phosphorylating FAM171A1. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
A polyphenol that inhibits certain protein kinases, potentially reducing competition for phosphorylation sites on FAM171A1, resulting in its increased activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A calcium ionophore that increases intracellular calcium levels, which can activate calcium-dependent kinases that phosphorylate FAM171A1, enhancing its activity. | ||||||
Zaprinast (M&B 22948) | 37762-06-4 | sc-201206 sc-201206A | 25 mg 100 mg | $103.00 $245.00 | 8 | |
A phosphodiesterase inhibitor which increases cAMP levels, leading to the activation of PKA that could phosphorylate and activate FAM171A1. | ||||||
Olomoucine | 101622-51-9 | sc-3509 sc-3509A | 5 mg 25 mg | $72.00 $274.00 | 12 | |
A cyclin-dependent kinase inhibitor that may influence phosphorylation cascades, potentially leading to enhanced phosphorylation and activation of FAM171A1. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $97.00 $254.00 | 36 | |
A protein synthesis inhibitor that activates stress-activated protein kinases (SAPKs) which could phosphorylate FAM171A1, resulting in its functional activation. | ||||||