EPM2AIP1 activators represent a class of compounds that engage with the regulatory mechanisms of glycogen metabolism through the modulation of the EPM2AIP1 protein. These activators include agents that could potentially elevate the functional activity of EPM2AIP1 by either enhancing its expression or by stabilizing the protein to ensure its prolonged presence and efficiency in the cell. Given EPM2AIP1's role in conjunction with other proteins like laforin and malin in carbohydrate metabolism, activators are envisaged to interface with these proteins, indirectly influencing EPM2AIP1's activity. Their mode of action involves upscaling the protein's interactions or optimizing the conditions under which EPM2AIP1 exerts its effects on the metabolic pathways it is involved in.
The chemical agents within this class are diverse in structure but unified in their functional endpoint-amplification of EPM2AIP1 activity. This activity may be achieved through a variety of cellular mechanisms, such as transcriptional regulation leading to increased production of EPM2AIP1, post-translational modifications that could extend the half-life of EPM2AIP1, or enhancement of the protein's interaction within the cellular milieu to support its metabolic role. Collectively, the chemicals categorized as EPM2AIP1 activators are characterized by their ability to favorably affect EPM2AIP1's operational capacity, ensuring that it performs optimally within the spectrum of its biological responsibilities. The compounds function as activators by integrating into the metabolic circuits that EPM2AIP1 influences, thereby establishing a conducive environment for the protein to carry out its functions more effectively.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin can promote glycogen synthesis, possibly affecting proteins associated with glycogen metabolism including EPM2AIP1. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Activates AMPK, which in turn can regulate enzymes and proteins involved in glycogen metabolism. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Stimulates adenylate cyclase, increasing cAMP, which could modulate proteins involved in glycogen metabolism. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
Activates AMPK and could indirectly influence glycogen metabolic pathways and associated proteins. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Affects glycogen synthase kinase-3 activity, potentially impacting glycogen metabolism and associated proteins. | ||||||
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $70.00 $215.00 | 26 | |
A glucose analog that can alter glycogen synthesis pathways, possibly influencing EPM2AIP1 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Modulates numerous signaling pathways, could indirectly influence proteins in glycogen metabolism. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Acts on various signaling pathways and may modulate proteins involved in carbohydrate metabolism. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects multiple signaling pathways and could influence regulatory proteins in glycogen storage and metabolism. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Impacts gene expression, which could have downstream effects on proteins involved in glycogen metabolism like EPM2AIP1. | ||||||