EMBP Activators
The class of EMBP activators comprises a diverse array of chemicals that directly or indirectly modulate EMBP expression through specific biochemical and cellular pathways, offering insights into the complex regulatory networks governing its dynamics. Each activator provides a unique avenue for targeted activation, shedding light on the intricate interplay between signaling pathways and EMBP modulation. AICAR and Dorsomorphin, both AMP-activated protein kinase (AMPK) activators, stand out as direct EMBP activators by influencing cellular energetics. AICAR mimics the effects of AMP, leading to AMPK activation, while Dorsomorphin promotes AMPK phosphorylation. These compounds provide a targeted approach to EMBP activation, offering insights into the regulatory networks governing cellular energy homeostasis and the direct modulation of EMBP expression through AMPK signaling.
GW501516, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, directly activates EMBP by modulating PPARδ signaling. Binding to PPARδ induces the transcriptional activation of genes involved in cellular metabolism, including EMBP. This direct activation through PPARδ modulation provides a specific and targeted approach to EMBP activation, offering insights into the regulatory networks governing metabolic signaling pathways and EMBP dynamics. Oltipraz, a nuclear factor erythroid 2-related factor 2 (Nrf2) activator, directly activates EMBP by modulating Nrf2 signaling. Activation of Nrf2 induces the transcriptional activation of antioxidant response element (ARE)-dependent genes, including EMBP. This direct activation through Nrf2 modulation provides a specific and targeted approach to EMBP activation through the regulation of oxidative stress response pathways.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR, an AMP-activated protein kinase (AMPK) activator, directly activates EMBP by influencing cellular energetics. AICAR mimics the effects of AMP, leading to AMPK activation. Activated AMPK then modulates downstream targets involved in EMBP regulation, providing a direct activation mechanism through the AMPK signaling pathway. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $96.00 $355.00 | 69 | |
BML-275 (Dorsomorphin), an AMPK activator, directly activates EMBP by promoting AMPK phosphorylation. By mimicking the effects of AMP, Dorsomorphin induces AMPK activation, influencing cellular energetics and downstream signaling pathways associated with EMBP regulation. This direct activation through AMPK modulation provides a targeted approach to EMBP activation. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $82.00 $179.00 | 28 | |
GW501516, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, directly activates EMBP by modulating PPARδ signaling. Binding to PPARδ, GW501516 induces the transcriptional activation of genes involved in cellular metabolism, including EMBP. This direct activation through PPARδ modulation provides a specific and targeted approach to EMBP activation through the regulation of metabolic signaling pathways. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 Inhibitor IX, a glycogen synthase kinase-3 beta (GSK-3β) inhibitor, indirectly activates EMBP by influencing the Wnt/β-catenin signaling pathway. Inhibition of GSK-3β stabilizes β-catenin, leading to its translocation into the nucleus and the activation of Wnt target genes, including EMBP. | ||||||
Oltipraz | 64224-21-1 | sc-205777 sc-205777A | 500 mg 1 g | $286.00 $622.00 | ||
Oltipraz, a nuclear factor erythroid 2-related factor 2 (Nrf2) activator, directly activates EMBP by modulating Nrf2 signaling. Activation of Nrf2 by Oltipraz induces the transcriptional activation of antioxidant response element (ARE)-dependent genes, including EMBP. This direct activation through Nrf2 modulation provides a specific and targeted approach to EMBP activation through the regulation of oxidative stress response pathways. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $184.00 $741.00 $1076.00 $3417.00 $5304.00 | 23 | |
A-769662, an AMPK activator, directly activates EMBP by promoting AMPK phosphorylation. Mimicking the effects of AMP, A-769662 induces AMPK activation, influencing cellular energetics and downstream signaling pathways associated with EMBP regulation. This direct activation through AMPK modulation provides a targeted approach to EMBP activation, offering insights into the regulatory networks governing cellular energy homeostasis and EMBP dynamics. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin, an AMPK activator, directly activates EMBP by promoting AMPK phosphorylation. Mimicking the effects of AMP, Metformin induces AMPK activation, influencing cellular energetics and downstream signaling pathways associated with EMBP regulation. This direct activation through AMPK modulation provides a targeted approach to EMBP activation, offering insights into the regulatory networks governing cellular energy homeostasis and EMBP dynamics. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin, a natural flavonoid, indirectly activates EMBP by influencing the NF-κB signaling pathway. Luteolin inhibits NF-κB activation, leading to decreased inflammation and cellular stress. This downregulation of NF-κB indirectly activates EMBP, as its expression is influenced by the anti-inflammatory effects of NF-κB inhibition. This indirect activation through NF-κB modulation provides insights into the complex interplay between inflammatory signaling and EMBP dynamics. | ||||||
Dihydrocapsaicin | 19408-84-5 | sc-202578 sc-202578A | 10 mg 50 mg | $52.00 $156.00 | 1 | |
Dihydrocapsaicin, a transient receptor potential vanilloid 1 (TRPV1) agonist, directly activates EMBP by modulating TRPV1 signaling. Activation of TRPV1 by Dihydrocapsaicin induces intracellular calcium influx and downstream signaling events that influence EMBP expression. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine, an AMPK activator, directly activates EMBP by promoting AMPK phosphorylation. Mimicking the effects of AMP, Berberine induces AMPK activation, influencing cellular energetics and downstream signaling pathways associated with EMBP regulation. This direct activation through AMPK modulation provides a targeted approach to EMBP activation, offering insights into the regulatory networks governing cellular energy homeostasis and EMBP dynamics. | ||||||