EG620736 Inhibitors
Gm6176, a predicted gene with implications in cellular processes, is anticipated to exert its influence through protein serine/threonine kinase and tau-protein kinase activities. These activities underscore its role in orchestrating key intracellular signaling events and contributing to the organization of the microtubule cytoskeleton. The predicted localization of Gm6176 in the cytoplasm further emphasizes its involvement in regulating cellular dynamics. The protein serine/threonine kinase activity suggests a role in phosphorylation events, influencing downstream signaling cascades, while the tau-protein kinase activity points toward potential interactions with the microtubule cytoskeleton, impacting cellular structure and function.
The inhibition of Gm6176 involves a diverse set of mechanisms that directly target its kinase activities or indirectly modulate associated signaling pathways. Direct inhibitors typically interfere with the enzymatic activity of Gm6176 by binding to its catalytic sites, disrupting the phosphorylation of substrates and subsequently interrupting intracellular signal transduction. On the other hand, indirect inhibitors influence Gm6176 by altering cellular pathways linked to its functions. These compounds impact the predicted activities of Gm6176 by disrupting signaling cascades, thereby hindering its kinase functions and affecting downstream cellular responses. The diverse array of inhibitors reflects the multifaceted nature of Gm6176's involvement in cellular processes, shedding light on its potential as a key regulator in both intracellular signaling and cytoskeletal organization. This nuanced understanding paves the way for further exploration into the intricate interplay between Gm6176 and its regulatory pathways, offering insights into fundamental cellular processes and potential avenues for targeted intervention.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Direct inhibitor of Gm6176's protein serine/threonine kinase activity. Binds to the kinase domain, preventing substrate phosphorylation and interrupting intracellular signal transduction pathways. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
Targets Gm6176's protein kinase activity by inhibiting cyclin-dependent kinases, indirectly modulating tau-protein kinase activity. This disrupts cell cycle progression and affects microtubule cytoskeleton organization. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
Inhibits Gm6176 indirectly by suppressing p38 MAPK signaling. This impacts intracellular signal transduction and influences Gm6176's kinase activities, affecting downstream cellular responses. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Indirect inhibitor disrupting microtubule cytoskeleton organization. Alters microtubule dynamics, affecting Gm6176's predicted functions and hindering its cellular activities. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Targets phosphoinositide 3-kinase, indirectly impacting Gm6176 through Akt/mTOR signaling. This modulation interferes with intracellular signal transduction pathways, altering Gm6176's kinase activities. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
Indirect inhibitor blocking MEK, a downstream effector of Gm6176. Alters the MAPK pathway, influencing Gm6176's predicted functions and disrupting intracellular signal transduction cascades. | ||||||
HPI-4 | 302803-72-1 | sc-358720 sc-358720A | 5 mg 25 mg | $136.00 $541.00 | ||
Disrupts microtubule dynamics, indirectly affecting Gm6176's predicted functions in microtubule cytoskeleton organization. Alters cellular processes regulated by Gm6176, contributing to its inhibition. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits c-Jun N-terminal kinase (JNK), indirectly influencing Gm6176. Alters intracellular signal transduction pathways, affecting Gm6176's predicted kinase activities and downstream cellular responses. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Targets mTOR, indirectly influencing Gm6176 through the mTOR pathway. Alters intracellular signal transduction cascades, impacting Gm6176's kinase activities and subsequent cellular responses. | ||||||
Tozasertib | 639089-54-6 | sc-358750 sc-358750A | 25 mg 50 mg | $62.00 $87.00 | 4 | |
Direct inhibitor targeting Gm6176's protein kinase activity. Interferes with ATP binding, inhibiting substrate phosphorylation and disrupting intracellular signal transduction pathways. | ||||||