Date published: 2026-4-1

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EG435949 Inhibitors

EG435949 inhibitors represent a chemical class of compounds primarily known for their ability to modulate specific biological pathways through inhibition of their target proteins or enzymes. These inhibitors are characterized by a core scaffold that interacts with particular active sites within their target molecules, blocking the normal activity and causing downstream effects on cellular signaling and function. Structurally, EG435949 inhibitors often contain multiple aromatic rings, fused or linked via flexible linkers, which allow the molecule to achieve a conformation optimal for binding to its target. The side chains and substituents on these rings are usually designed to enhance the affinity, specificity, and binding kinetics of the inhibitor to its biological target. This chemical class is notable for its high degree of selectivity, where the substituents are meticulously chosen to improve the interaction with the binding site while minimizing off-target effects.

These compounds typically exhibit a diverse range of chemical properties, including solubility and lipophilicity, which can be fine-tuned to optimize their bioavailability and metabolic stability. Due to their high binding specificity, EG435949 inhibitors are valuable for studying protein-protein interactions and biochemical pathways in a variety of cellular systems. The development of these inhibitors often involves structure-activity relationship (SAR) studies, where modifications to their chemical structure lead to variations in biological activity, providing insights into their binding mechanisms and potency. Additionally, their versatility in structural design allows for modification to adapt to different targets, making EG435949 inhibitors a versatile tool in molecular biology for probing specific pathways and elucidating the role of various proteins in complex cellular networks.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Wortmannin is a potent PI3-kinase inhibitor, disrupting the PI3K/Akt pathway. Vmn1r244 is intricately connected to this pathway, and Wortmannin indirectly inhibits Vmn1r244 by perturbing downstream signaling events, leading to alterations in Vmn1r244 expression and function within the cellular context.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 is a selective PI3-kinase inhibitor, perturbing the PI3K/Akt pathway. Vmn1r244 is associated with this pathway, and LY294002 indirectly inhibits Vmn1r244 by influencing downstream signaling cascades, causing modifications in Vmn1r244 expression and function within the cellular milieu.

PD 169316

152121-53-4sc-204168
sc-204168A
sc-204168B
sc-204168C
1 mg
5 mg
10 mg
25 mg
$88.00
$156.00
$281.00
$461.00
3
(1)

SB203580 is a p38 MAPK inhibitor, perturbing MAPK signaling. Vmn1r244, being downstream in this pathway, is indirectly influenced by SB203580. The inhibition occurs through perturbation of p38 MAPK signaling, leading to modifications in Vmn1r244 expression and function within the cellular context.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

PD98059 is a MEK inhibitor, disrupting the MAPK pathway. Vmn1r244 is positioned downstream in this pathway, and its activity is indirectly influenced by PD98059. The inhibition occurs through perturbation of the MAPK signaling cascade, leading to modifications in Vmn1r244 expression and function within the cellular milieu.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

SP600125 is a JNK inhibitor, affecting the JNK signaling pathway. Vmn1r244 is indirectly influenced by SP600125, positioned downstream in the JNK pathway. The inhibition occurs through perturbation of the JNK cascade, leading to modifications in Vmn1r244 expression and function within the cellular context.

Calyculin A

101932-71-2sc-24000
sc-24000A
10 µg
100 µg
$163.00
$800.00
59
(3)

Calyculin A is a potent protein phosphatase inhibitor, disrupting cellular phosphorylation dynamics. Vmn1r244 activity is modulated by phosphorylation events, and Calyculin A indirectly inhibits Vmn1r244 by influencing protein phosphatase activity, resulting in altered phosphorylation patterns that impact Vmn1r244 function within the cell.