EF-CAB7 Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
As a protein kinase C (PKC) activator, PMA influences signaling pathways that PKC participates in, which includes the regulation of EF-CAB7 through PKC-mediated phosphorylation events. Enhanced PKC activity can lead to the phosphorylation and subsequent inhibition of EF-CAB7's function in calcium signaling. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin raises intracellular cAMP levels, which indirectly can diminish EF-CAB7 activity by activating PKA. PKA can phosphorylate proteins that regulate calcium signaling, thereby decreasing EF-CAB7's functional role in these pathways. | ||||||
Chelerythrine chloride | 3895-92-9 | sc-3547 sc-3547A | 5 mg 25 mg | $88.00 $311.00 | 17 | |
As a PKC inhibitor, chelerythrine can decrease PKC-mediated pathways, and thus potentially inhibit the function of EF-CAB7 if it's regulated by PKC-dependent phosphorylation. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Gö 6983 is a broad-spectrum PKC inhibitor that can prevent PKC-mediated phosphorylation, which may lead to the inhibition of EF-CAB7 if its function is modulated by PKC signaling. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
2-APB acts as an inhibitor of IP3 receptors and store-operated calcium (SOC) channels, which can lead to reduced calcium signaling and thereby inhibit EF-CAB7 if it is involved in calcium-dependent pathways. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Verapamil is a calcium channel blocker that can diminish calcium influx. If EF-CAB7 is involved in pathways dependent on calcium signaling, its function would be indirectly inhibited by verapamil. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin serves as a SERCA pump inhibitor, leading to the depletion of ER calcium stores and alteration of calcium signaling. This can indirectly inhibit EF-CAB7 if it operates within these calcium-dependent pathways. | ||||||
Ryanodine | 15662-33-6 | sc-201523 sc-201523A | 1 mg 5 mg | $219.00 $765.00 | 19 | |
Ryanodine locks ryanodine receptors in a sub-conductive state, disrupting calcium release from the sarcoplasmic and endoplasmic reticulum, which may indirectly inhibit EF-CAB7 if it's associated with these signaling mechanisms. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
Nifedipine is a calcium channel blocker that can reduce calcium influx. If EF-CAB7 is involved in calcium-dependent signaling, then its function could be indirectly inhibited by nifedipine. | ||||||
Calmidazolium chloride | 57265-65-3 | sc-201494 sc-201494A | 10 mg 50 mg | $153.00 $600.00 | 27 | |
Calmidazolium chloride is a calmodulin antagonist that can inhibit calmodulin-dependent kinase (CaMK) activity. If EF-CAB7 is regulated by CaMK, this compound could indirectly inhibit its function. | ||||||