EB3 Activators
EB3 Activators encompass a range of compounds that indirectly influence the activity of EB3, primarily by modulating microtubule dynamics, crucial in various cellular processes. Paclitaxel and Epothilone B, by stabilizing microtubules, enhance EB3's role in facilitating microtubule growth and stability, which is pivotal in cell division and neuronal development. Similarly, Taxol, a synonymous name for Paclitaxel, contributes to this enhancement by promoting microtubule polymerization, thereby supporting EB3's function in microtubule dynamics. Nocodazole and Vinblastine, though they disrupt and interfere with microtubule assembly, indirectly augment EB3 activity. This enhancement occurs as EB3 is crucial in microtubule growth and stability, especially during cell division and in neuronal growth, processes that are significantly influenced by microtubule dynamics.
Additionally, Vincristine, Colchicine, and Podophyllotoxin, by altering microtubule assembly and dynamics, contribute to the enhancement of EB3's function. These agents highlight the critical role of EB3 in maintaining microtubule integrity, particularly in neuronal development and cell division. Eribulin, Peloruside A, and Laulimalide, through their effects on microtubule stabilization and growth, also support the functionality of EB3. This support is crucial in processes such as intracellular transport and neuronal growth, where microtubule dynamics play a fundamental role. Lastly, Combretastatin A4, by disrupting microtubules, underscores the significance of EB3 in microtubule regulation. Collectively, these EB3 Activators, through their targeted impact on microtubule dynamics, facilitate the enhancement of EB3 mediated functions in various cellular processes, emphasizing the intricate interplay between microtubule dynamics and EB3 activity in cells.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Paclitaxel stabilizes microtubules and enhances microtubule polymerization. This stabilization indirectly enhances EB3 activity by promoting microtubule dynamics, a process where EB3 is crucial, especially in facilitating microtubule growth and the stability at the plus ends in various cell types. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole disrupts microtubules and blocks their polymerization. By modulating microtubule dynamics, it indirectly enhances EB3 activity, as EB3 plays a significant role in microtubule growth and stability, particularly during cell division and intracellular transport. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Epothilone B stabilizes microtubules and promotes microtubule polymerization. This action indirectly enhances EB3 activity, as EB3 is involved in microtubule dynamics, playing a key role in the stability and growth of microtubules in cells, particularly in neurons and during cell division. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Colchicine binds to tubulin and inhibits microtubule polymerization. By influencing microtubule dynamics, it indirectly enhances the activity of EB3, particularly in processes like cell division and intracellular transport, where EB3 plays a significant role in microtubule growth and stabilization. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Podophyllotoxin inhibits microtubule assembly. By modulating microtubule dynamics, it indirectly enhances EB3's function in microtubule growth and stability, essential for processes like mitosis and intracellular transport, where EB3 plays a key role. | ||||||
Canertinib | 267243-28-7 | sc-207397 | 10 mg | $260.00 | 3 | |
Laulimalide stabilizes microtubules, similar to Paclitaxel and Epothilone B. This stabilization indirectly enhances EB3 activity in microtubule dynamics, crucial for neuronal development, intracellular transport, and cell division, where EB3 plays a significant role in microtubule growth. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $46.00 $81.00 | ||
Combretastatin A4 disrupts microtubules and inhibits their assembly. By affecting microtubule dynamics, it indirectly enhances EB3's function in microtubule growth and stability, essential in processes like angiogenesis, cell division, and intracellular transport, where EB3 is a key regulatory protein. | ||||||