Date published: 2025-12-10

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DRP1 Activators

Common DRP1 Activators include, but are not limited to Mdivi-1 CAS 338967-87-6, Carbonyl Cyanide m-Chlorophenylhydrazone CAS 555-60-2, Calcium CAS 7440-70-2, FCCP CAS 370-86-5 and L-Glutamic acid monosodium salt CAS 142-47-2.

DRP1 Activators represent a specialized category of chemical compounds distinguished by their unique capacity to modulate the activity of dynamin-related protein 1 (DRP1). This chemical class operates through specific interactions that involve enhancing the signaling pathways associated with DRP1, a GTPase enzyme critically involved in mitochondrial fission-a fundamental process in cellular dynamics. The pivotal role of DRP1 in regulating mitochondrial morphology, distribution, and quality control underscores its significance in various cellular functions, adding to the multifaceted landscape of cellular processes.

The mechanisms through which DRP1 Activators exert their influence involve precise molecular interactions capable of amplifying downstream effects within DRP1-mediated signaling. This modulation holds promise for contributing to the regulation of mitochondrial fission, cellular energy production, and the maintenance of mitochondrial homeostasis. The intricate details of how DRP1 Activators impact DRP1-related pathways remain subjects of ongoing scientific exploration. These endeavors not only deepen our understanding of cellular communication but also shed light on the intricate machinery governing mitochondrial dynamics-a complex and tightly regulated aspect of cellular function. The specific modes of engagement between DRP1 Activators and DRP1 highlight the significance of this chemical class in unraveling the complexities of cellular processes, offering applications across various scientific domains. As research continues to dissect the precise molecular interactions orchestrated by DRP1 Activators, they emerge as valuable tools for advancing our understanding of cellular regulation and contributing to the broader landscape of scientific knowledge.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mdivi-1

338967-87-6sc-215291
sc-215291B
sc-215291A
sc-215291C
5 mg
10 mg
25 mg
50 mg
$66.00
$124.00
$246.00
$456.00
13
(2)

Inhibits DRP1-mediated mitochondrial fission by preventing DRP1 recruitment, leading to elongated mitochondrial networks.

Carbonyl Cyanide m-Chlorophenylhydrazone

555-60-2sc-202984A
sc-202984
sc-202984B
100 mg
250 mg
500 mg
$75.00
$150.00
$235.00
8
(1)

Disrupts mitochondrial membrane potential, leading to DRP1-mediated fission through uncoupling oxidative phosphorylation.

Calcium

7440-70-2sc-252536
5 g
$209.00
(0)

Elevated cytosolic calcium levels trigger DRP1-mediated mitochondrial fission, participating in processes like apoptosis.

FCCP

370-86-5sc-203578
sc-203578A
10 mg
50 mg
$92.00
$348.00
46
(1)

Compounds like FCCP uncouple oxidative phosphorylation, activating DRP1-mediated mitochondrial fission.

L-Glutamic Acid

56-86-0sc-394004
sc-394004A
10 g
100 g
$291.00
$566.00
(0)

Elevated glutamate levels, an excitatory neurotransmitter, activate DRP1 and contribute to mitochondrial fragmentation.