Date published: 2026-5-6

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DR5 Antibodies

Santa Cruz Biotechnology provides a broad selection of DR5 monoclonal antibodies for advanced research in apoptosis and cell signaling pathways. DR5 monoclonal antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). DR5, also known as death receptor 5, plays a critical role in mediating apoptosis through its interaction with the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL). The receptor is essential for regulating cell death and has significant implications in cancer therapy, as it can selectively induce apoptosis in tumor cells while sparing normal cells. Understanding DR5 function is crucial for developing targeted treatments and improving therapeutic strategies in oncology. Researchers worldwide rely on DR5 monoclonal antibodies to investigate cellular mechanisms and pathways involved in programmed cell death. DR5 monoclonal antibodies enable detailed examination of receptor expression patterns across different tissue types and experimental conditions. The specificity and reliability of Santa Cruz Biotechnology monoclonal antibodies support researchers in advancing scientific understanding of apoptosis and cancer biology.

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DR5 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DR5 Antibody (D-6)

sc-166624mouse IgG1 κ48-76 (h)WB, IP, IF, ELISAh
36
(14)

DR5 Antibody (MD5-1)

sc-57086A. hamster IgG(m)FCMm
2
(1)

DR5 Antibody (7F4-F8-G11)

sc-517559mouse IgG(h)WB, IFm, r, h

new

(1)

DR5 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR5 CRISPR/Cas9 KO Plasmid (h)

sc-401002hGene KnockoutGFP
1
(0)

DR5 HDR Plasmid (h)

sc-401002-HDRhHomology Directed RepairPuromycin
1
(0)

DR5 Double Nickase Plasmid (h)

sc-401002-NIChGene KnockoutPuromycin
1
(0)

DR5 Double Nickase Plasmid (h2)

sc-401002-NIC-2hGene KnockoutPuromycin
1
(0)

DR5 CRISPR/Cas9 KO Plasmid (m2)

sc-423438-KO-2m2Gene KnockoutGFP0
(0)

DR5 HDR Plasmid (m2)

sc-423438-HDR-2mHomology Directed RepairPuromycin0
(0)

DR5 Double Nickase Plasmid (m)

sc-423438-NICmGene KnockoutPuromycin0
(0)

DR5 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR5 CRISPR Activation Plasmid (h)

sc-401002-ACThGene ActivationPuro, Blast, Hygro
1
(0)

DR5 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR5 siRNA (h)

sc-40237hGene SilencingN/A
51
(1)

DR5 shRNA Plasmid (h)

sc-40237-SHhGene SilencingPuromycin
51
(1)

DR5 shRNA (h) Lentiviral Particles

sc-40237-VhGene SilencingPuromycin
51
(1)

DR5 siRNA (m)

sc-40238mGene SilencingN/A
2
(0)

DR5 shRNA Plasmid (m)

sc-40238-SHmGene SilencingPuromycin
2
(0)

DR5 shRNA (m) Lentiviral Particles

sc-40238-VmGene SilencingPuromycin
2
(0)