Date published: 2025-10-15

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DnaJC15 Inhibitors

DnaJC15 Inhibitors are a category of chemical compounds meticulously crafted to intricately modulate the operational dynamics of the DNAJC15 protein. DNAJC15, an integral constituent of the DNAJ/HSP40 protein family, shoulders pivotal responsibilities across diverse cellular functions including orchestrating protein folding processes, facilitating chaperone-mediated activities, and orchestrating responses to a spectrum of cellular stresses. The very essence of these inhibitors lies in their purposeful disruption of the finely tuned activities of DNAJC15, possibly enacted through precise interactions with its active domains or the conformational architecture that underpins its functionality. By engendering perturbations within the operational scope of DNAJC15, these inhibitors endeavor to reverberate across the intricate meshwork of molecular crosstalk and cellular pathways that lay enmeshed with DNAJC15's multifaceted role. A pivotal pursuit is to fathom the manifold interactions DNAJC15 engages in, further deciphering the orchestration of cellular processes it shapes in conjunction with a retinue of partner molecules.

Consequently, the strategic design and implementation of DnaJC15 inhibitors stand to unravel hitherto concealed intricacies of cell biology, potentially yielding insights into the cogs and gears of molecular physiology. As the frontier of scientific understanding advances, the prospective vistas carved open by DnaJC15 inhibitors may broaden. Insights gleaned from these inhibitors could potentially illuminate avenues ranging from unveiling fundamental cellular processes to deciphering the intricacies of molecular communication networks. Amid this journey of discovery, the sole focus rests on comprehending the mechanistic dance choreographed by DNAJC15 and its ensemble of molecular collaborators. In elucidating these enigmatic molecular symphonies, DnaJC15 inhibitors resonate as vital instruments poised to decipher the cryptic language through which cells communicate, adapt, and function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

JG-98

1456551-16-8sc-507517
5 mg
$220.00
(0)

This compound was reported as a selective inhibitor of HSP40, which is a member of the HSP40/DNAJ family that includes DNAJC15.

VER 155008

1134156-31-2sc-358808
sc-358808A
10 mg
50 mg
$199.00
$825.00
9
(1)

While not specific to DNAJC15, this compound is known as a heat shock protein 70 (HSP70) inhibitor and might indirectly affect DNAJ/HSP40 proteins.

JIB 04

199596-05-9sc-397040
20 mg
$177.00
(0)

This compound has been reported to inhibit the activity of HSP70 and HSP90, which are related to the chaperone machinery involving DNAJ/HSP40 proteins.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

A naturally occurring flavonoid that has been shown to have inhibitory effects on HSP70 and HSP90, potentially impacting DNAJ/HSP40 proteins indirectly.

Withaferin A

5119-48-2sc-200381
sc-200381A
sc-200381B
sc-200381C
1 mg
10 mg
100 mg
1 g
$127.00
$572.00
$4090.00
$20104.00
20
(1)

A compound found in Withania somnifera that has shown inhibitory effects on HSP70 and might influence DNAJ/HSP40 activity.