The chemical class referred to as DNA Pol δ 4 Activators comprises a diverse set of molecules that have been observed to induce the expression or enhance the activity of DNA polymerase delta 4 (DNA Pol δ 4). These activators may function through various biochemical and cellular mechanisms, such as modulating gene transcription, affecting cell cycle progression, or interacting with upstream signaling pathways. For instance, some of these activators may influence epigenetic factors like DNA methylation or histone modifications to upregulate DNA Pol δ 4 expression. Others may work by triggering specific cellular receptors or by modulating the activity of kinases and other enzymes that have a role in regulating DNA Pol δ 4.
Interestingly, the range of compounds in this class is quite broad and includes not only small organic molecules but also metal ions and specific vitamins. The molecular diversity of this class reflects the complexity of DNA replication and repair mechanisms in which DNA Pol δ 4 is involved. While the primary focus of interest in this chemical class is its interaction with DNA Pol δ 4, it's crucial to note that these compounds usually have multiple cellular targets and can influence various other biochemical pathways. As a result, their action could be seen as part of a broader cellular response, which might include responses to oxidative stress, DNA damage, or other cellular signals. The characterization of these activators can provide valuable insights into the cellular functions of DNA Pol δ 4 as well as the intricate biochemical pathways that regulate its activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone is known to affect gene transcription and could influence the upregulation of DNA Pol δ 4 in certain cellular contexts. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $70.00 $160.00 $290.00 | 2 | |
Vitamin D3 has roles in cellular differentiation and DNA repair, potentially leading to increased expression of DNA Pol δ 4. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
β-estradiol may affect DNA Pol δ 4 expression through estrogen receptor-mediated pathways. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $47.00 | ||
Zinc is essential for many cellular processes including DNA repair, and its presence may induce DNA Pol δ 4 expression. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $87.00 $224.00 | ||
This compound can influence gene expression and cell cycle control, potentially leading to the upregulation of DNA Pol δ 4. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is known to affect multiple cellular signaling pathways and could potentially induce DNA Pol δ 4 expression. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin affects various cellular receptors and pathways, which could lead to the induction of DNA Pol δ 4. | ||||||
Selenium | 7782-49-2 | sc-250973 | 50 g | $61.00 | 1 | |
Selenium can affect oxidative stress responses, potentially leading to increased expression of DNA Pol δ 4. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $61.00 $122.00 | 1 | |
Niacin participates in various metabolic pathways and could play a role in the induction of DNA Pol δ 4. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $26.00 $50.00 $99.00 $150.00 $1887.00 | 40 | |
Luteolin has antioxidant and anti-inflammatory properties, potentially affecting DNA Pol δ 4 expression. | ||||||