Date published: 2025-10-22

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DMRT1 Inhibitors

DMRT1 inhibitors belong to a specific chemical class that targets the protein DMRT1, which plays a crucial role in cellular processes. DMRT1, short for Doublesex and mab-3-related transcription factor 1, is a transcription factor known to regulate gene expression involved in various biological functions. The inhibitors designed to interact with DMRT1 aim to modulate its activity and prevent its normal function. These inhibitors typically possess specific chemical structures that enable them to bind to DMRT1, either at its active site or at other regulatory regions, thereby disrupting its normal function.

The inhibition of DMRT1 is of particular interest to researchers due to its diverse involvement in essential processes such as embryogenesis, gonad development, and cell differentiation. By blocking DMRT1 activity, these inhibitors may offer valuable insights into the underlying mechanisms that govern these processes. Additionally, DMRT1 inhibitors have the potential to act as valuable research tools, aiding in the elucidation of DMRT1's interactions with other cellular components and its downstream effects on gene expression.It is essential to continue investigating DMRT1 inhibitors, as they could hold promise in expanding our understanding of cellular and developmental biology. By studying the effects of these inhibitors in experimental models and controlled environments, scientists can gain critical knowledge about the intricacies of DMRT1 function. Understanding the nuances of DMRT1 inhibition will contribute significantly to advancing our knowledge of molecular biology and its impact on various biological processes.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Indole-3-carbinol

700-06-1sc-202662
sc-202662A
sc-202662B
sc-202662C
sc-202662D
1 g
5 g
100 g
250 g
1 kg
$38.00
$60.00
$143.00
$306.00
$1012.00
5
(1)

A natural compound found in cruciferous vegetables like broccoli and cabbage. It has been shown to inhibit DMRT1 expression and interfere with germ cell development.

Dimethyl Sulfoxide (DMSO)

67-68-5sc-202581
sc-202581A
sc-202581B
100 ml
500 ml
4 L
$30.00
$115.00
$900.00
136
(6)

Though not a specific DMRT1 inhibitor, DMSO has been reported to influence DMRT1 expression in certain contexts.

Methotrexate

59-05-2sc-3507
sc-3507A
100 mg
500 mg
$92.00
$209.00
33
(5)

An anti-folate drug used in cancer chemotherapy, which has been shown to inhibit DMRT1 and impair germ cell development in certain studies.