Date published: 2026-4-1

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DGCR6L Inhibitors

DDX26B Inhibitors constitute a specific class of chemical compounds designed to selectively impede the activity of the DDX26B enzyme. DDX26B, also known as DEAD-box helicase 26B, belongs to the broader family of DEAD-box helicases, which are involved in RNA metabolism and contribute to various aspects of RNA processing, including transcription, splicing, and translation. The development of inhibitors targeting DDX26B is pivotal for scientific exploration, offering specialized tools to elucidate the molecular functions and regulatory roles associated with this particular helicase. As a member of the DEAD-box helicase family, DDX26B likely plays a role in unwinding RNA secondary structures, facilitating RNA-protein interactions, and modulating the dynamic landscape of cellular RNA processing events.

The synthesis and optimization of DDX26B inhibitors necessitate a thorough understanding of the enzyme's structural features and its interactions within cellular pathways. These inhibitors are meticulously designed for specificity, aiming to selectively bind to key regions of DDX26B and interfere with its normal helicase activities. By utilizing DDX26B inhibitors in experimental settings, researchers can investigate the consequences of enzyme inhibition on RNA processing dynamics, shedding light on the specific substrates and molecular pathways governed by DDX26B. The study of DDX26B inhibitors contributes to the broader comprehension of cellular RNA metabolism, providing insights into the intricate molecular mechanisms that regulate gene expression and RNA-related processes in cells.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

α-Amanitin inhibits RNA polymerase II, hindering transcription and preventing the synthesis of DGCR6L mRNA.

Puromycin dihydrochloride

58-58-2sc-108071
sc-108071B
sc-108071C
sc-108071A
25 mg
250 mg
1 g
50 mg
$42.00
$214.00
$832.00
$66.00
394
(16)

Puromycin induces premature termination of protein synthesis, impacting translation and lowering DGCR6L levels.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Actinomycin C1 binds to DNA and inhibits transcription, leading to a decrease in the expression of DGCR6L.

Cordycepin

73-03-0sc-203902
10 mg
$101.00
5
(1)

Cordycepin interferes with mRNA synthesis, impacting transcription and contributing to the downregulation of DGCR6L.

Flavopiridol Hydrochloride

131740-09-5sc-207687
10 mg
$317.00
(2)

Flavopiridol is a cyclin-dependent kinase inhibitor, preventing the phosphorylation of RNA polymerase II and inhibiting DGCR6L transcription.

Ellipticine

519-23-3sc-200878
sc-200878A
10 mg
50 mg
$145.00
$569.00
4
(1)

Ellipticine intercalates into DNA, inhibiting transcription and leading to a decrease in the expression of DGCR6L.

Streptonigrin

3930-19-6sc-500892
sc-500892A
1 mg
5 mg
$104.00
$364.00
1
(1)

Streptolydigin inhibits bacterial RNA polymerase, indirectly affecting DGCR6L expression by interfering with transcription.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$69.00
$266.00
8
(1)

Mycophenolic acid inhibits inosine monophosphate dehydrogenase, indirectly affecting DGCR6L expression by disrupting purine synthesis.

Blasticidin S Hydrochloride

3513-03-9sc-204655A
sc-204655
25 mg
100 mg
$367.00
$520.00
20
(2)

Blasticidin S induces premature termination during translation, inhibiting protein synthesis and reducing DGCR6L levels.