Date published: 2026-4-5

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Desmoplakin Antibodies

Santa Cruz Biotechnology features a diverse variety of Desmoplakin monoclonal antibodies for research in cell adhesion and cytoskeletal integrity. Desmoplakin Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Desmoplakin is a crucial component of desmosomes, playing a significant role in maintaining the structural integrity of tissues by anchoring intermediate filaments to cell membranes. Its function is vital in cardiac and epithelial tissues, where it contributes to cell-cell adhesion and mechanical stability. Dysregulation of Desmoplakin has been implicated in various diseases, including cardiomyopathies and skin disorders, highlighting its importance in both health and disease. Understanding Desmoplakin's molecular mechanisms can provide insights into potential therapeutic strategies for related pathologies. Investigating Desmoplakin's role in tissue development and maintenance continues to reveal new aspects of cellular organization. Research into Desmoplakin expression patterns helps identify biomarkers for disease progression and treatment response. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of Desmoplakin's role in health and disease.

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Desmoplakin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

desmoplakin I/II Antibody (A-1)

sc-390975mouse IgG1 κ79-300 (h)WB, IP, IF, IHC(P), ELISAh
16
(7)

desmoplakin I/II Antibody (B-1)

sc-365981mouse IgG1 κ91-125 (h)WB, IP, IF, ELISAh
1
(1)

desmoplakin I/II Antibody (G-2)

sc-373789mouse IgG1 κ2745-2781 (h)WB, IP, IF, ELISAh

new

(1)

Desmoplakin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II CRISPR/Cas9 KO Plasmid (h)

sc-400818hGene KnockoutGFP0
(0)

desmoplakin I/II Double Nickase Plasmid (h)

sc-400818-NIChGene KnockoutPuromycin0
(0)

desmoplakin I/II Double Nickase Plasmid (h2)

sc-400818-NIC-2hGene KnockoutPuromycin0
(0)

desmoplakin I/II CRISPR/Cas9 KO Plasmid (m)

sc-430943mGene KnockoutGFP0
(0)

Desmoplakin CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II CRISPR Activation Plasmid (h)

sc-400818-ACThGene ActivationPuro, Blast, Hygro0
(0)

Desmoplakin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II siRNA (h)

sc-43724hGene SilencingN/A0
(0)

desmoplakin I/II shRNA Plasmid (h)

sc-43724-SHhGene SilencingPuromycin0
(0)

desmoplakin I/II shRNA (h) Lentiviral Particles

sc-43724-VhGene SilencingPuromycin0
(0)

desmoplakin I/II siRNA (m)

sc-45911mGene SilencingN/A0
(0)

desmoplakin I/II shRNA Plasmid (m)

sc-45911-SHmGene SilencingPuromycin0
(0)

desmoplakin I/II shRNA (m) Lentiviral Particles

sc-45911-VmGene SilencingPuromycin0
(0)