Date published: 2026-1-9

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Decorin Inhibitors

Decorin is a small leucine-rich proteoglycan that plays a vital role in the regulation of cellular processes, including proliferation, migration, and tissue organization. Decorin interacts with various extracellular matrix components and cell surface receptors, modulating signaling pathways and influencing cellular behavior. Decorin inhibitors, therefore, are chemical compounds designed to specifically target and modulate the activity of decorin, influencing its interaction with other molecules and cellular processes. These inhibitors can vary widely in their structure, origin, and mechanism of action, depending on the specific aspect of decorin function they are designed to target. The design and development of decorin inhibitors require a comprehensive understanding of decorin's molecular structure, function, and its role in cellular processes. These inhibitors could be small molecules, peptides, or other forms of bioactive compounds. Their mode of action might involve direct binding to decorin, interfering with its ability to interact with other proteins or cell surface receptors, or modulating its expression levels within cells. The specificity and efficacy of these inhibitors are crucial, as off-target effects could lead to unintended consequences, given decorin's involvement in various cellular processes. The study of decorin inhibitors is a complex field, intertwining aspects of biochemistry, cell biology, and molecular biology, aiming to elucidate the intricate web of interactions and signaling pathways in which decorin is involved.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

This compound is a cytidine analog and acts as a DNA methyltransferase inhibitor, potentially affecting gene expression, including that of Decorin, by altering methylation patterns on the DNA.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

Trichostatin A is a histone deacetylase inhibitor, which could lead to changes in chromatin structure and subsequently influence the transcription of various genes, including Decorin.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$31.00
$47.00
$84.00
$222.00
19
(3)

Sodium butyrate acts as a histone deacetylase inhibitor and can modify gene expression. Its potential role in inhibiting Decorin expression may be through alterations in chromatin accessibility.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is known for its anti-inflammatory properties and has the potential to modulate gene expression. It might inhibit Decorin expression by affecting signaling pathways and transcription factors.

Hydroxyurea

127-07-1sc-29061
sc-29061A
5 g
25 g
$78.00
$260.00
18
(1)

Hydroxyurea inhibits ribonucleotide reductase, potentially affecting DNA synthesis and cell cycle progression. This might influence the expression of various genes, including Decorin.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits mTOR, a central regulator of cell growth and metabolism. By doing so, it might influence the expression of various genes, including Decorin, as part of its role in cellular homeostasis.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG is a major component of green tea and has antioxidant properties. It has the potential to modulate gene expression and might influence Decorin expression through its effects on signaling pathways.

2-Deoxy-D-glucose

154-17-6sc-202010
sc-202010A
1 g
5 g
$70.00
$215.00
26
(2)

2-Deoxy-D-glucose is a glucose analog and can inhibit glycolysis. By affecting cellular metabolism, it might influence the expression of various genes, including Decorin, as part of the cellular response to metabolic stress.