DDX19A Activators
DDX19A activators constitute a class of chemicals that indirectly modulate the activity of the DEAD-box helicase 19A (DDX19A), a protein involved in RNA metabolism and processing. Several key members of this class include adenosine triphosphate (ATP) and adenosine diphosphate (ADP). ATP, as a cofactor, provides the necessary energy for DDX19A's helicase activity by facilitating the unwinding of RNA or DNA duplexes. In contrast, ADP, generated during ATP hydrolysis, can indirectly regulate DDX19A by acting as a signal for its ATPase activity, an essential component of its helicase function.
Guanosine triphosphate (GTP), similar to ATP, indirectly influences DDX19A by modulating cellular signaling pathways related to gene expression and RNA metabolism. Moreover, chemical inhibitors of RNA helicases, while not direct activators, indirectly enhance DDX19A activity by reducing competition from other helicases, allowing DDX19A to perform its unwinding functions more effectively. These DDX19A activators contribute to the intricate regulation of RNA processing and metabolism within the cell by indirectly influencing DDX19A's participation in these critical processes.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $38.00 $74.00 | 9 | |
ATP is a crucial cofactor for many helicases, including DDX19A. It provides the energy needed for helicase activity by fueling the unwinding of RNA or DNA duplexes. | ||||||
Adenosine-5′-Diphosphate, free acid | 58-64-0 | sc-291846 sc-291846A sc-291846B sc-291846C sc-291846D sc-291846E | 100 mg 500 mg 1 g 10 g 100 g 500 g | $77.00 $180.00 $312.00 $924.00 $4596.00 $9186.00 | 1 | |
ADP, the product of ATP hydrolysis, can indirectly influence DDX19A by serving as a regulatory signal for its ATPase activity, which is essential for its helicase function. | ||||||
Guanosine 5′-Triphosphate, Disodium Salt | 56001-37-7 | sc-295030 sc-295030A | 50 mg 250 mg | $163.00 $321.00 | ||
GTP, a nucleotide similar to ATP, can indirectly influence DDX19A by modulating cellular signaling pathways involved in gene expression and RNA metabolism. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-FU interferes with RNA and DNA synthesis. By affecting nucleotide metabolism, it may indirectly influence DDX19A's ability to interact with RNA molecules. | ||||||
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $45.00 $56.00 $183.00 | 142 | |
Sodium orthovanadate is a general protein phosphatase inhibitor. It can indirectly affect DDX19A by modulating cellular signaling pathways related to RNA metabolism. | ||||||
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $39.00 $45.00 $98.00 | 26 | |
Sodium fluoride is another protein phosphatase inhibitor. It can indirectly activate DDX19A by affecting cellular processes associated with RNA metabolism and phosphorylation. | ||||||