D4Ertd22e Inhibitors are a class of chemicals that can indirectly inhibit the functional activity of D4Ertd22e by influencing the cellular processes or signaling pathways it is involved in. These include inhibitors of the PI3K-Akt pathway, such as LY294002, Wortmannin, and Rapamycin, which inhibit the activation of Akt, a key component of this pathway. This inhibition can indirectly decrease the functional activity of D4Ertd22e, which is known to be involved in the PI3K-Akt pathway.
Other D4Ertd22e inhibitors target the MAPK pathway, a signaling route where D4Ertd22e is believed to play a role. These inhibitors, including SB203580, PD98059, and SP600125, halt the functional activity of molecules in the MAPK pathway, which leads to the functional inhibition of D4Ertd22e. Furthermore, inhibitors such as PP2 and Genistein, which inhibit Src family kinases and tyrosine kinases respectively, leads to the functional inhibition of D4Ertd22e is involved in the same cellular processes. Finally, inhibitors like U0126, Akti-1/2, Y-27632, and KN-93target MEK in the MAPK pathway, Akt in the PI3K-Akt pathway, ROCK, and CaMKII respectively.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A potent PI3K inhibitor that prevents the activation of Akt. Given that D4Ertd22e is involved in the PI3K-Akt signaling pathway, inhibiting the pathway could indirectly decrease the functional activity of D4Ertd22e. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Similar to LY294002, Wortmannin is also a PI3K inhibitor. It hampers the PI3K-Akt pathway, which can indirectly lead to the functional inhibition of D4Ertd22e. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A potent inhibitor of p38 MAPK. This compound inhibits the p38 MAPK pathway, which D4Ertd22e is believed to be involved in. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
An inhibitor of MEK, the upstream kinase of ERK in the MAPK pathway. As D4Ertd22e is involved in the MAPK pathway, inhibition of this pathway can lead to decreased functional activity of D4Ertd22e. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
It inhibits mTOR, a key player in the PI3K-Akt pathway. By halting this pathway, Rapamycin can indirectly result in the functional inhibition of D4Ertd22e. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, a component of the MAPK pathway. This could potentially lead to functional inhibition of D4Ertd22e. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 inhibits Src family kinases. This could potentially lead to the functional inhibition of D4Ertd22e if it is involved in the same cellular processes. | ||||||
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $208.00 $270.00 | 29 | |
It is a selective Akt1/2 inhibitor. Given that D4Ertd22e is involved in the PI3K-Akt signaling pathway, inhibiting Akt could indirectly decrease the functional activity of D4Ertd22e. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A potent inhibitor of Rho-associated coiled-coil forming protein serine/threonine kinase (ROCK). This could potentially lead to functional inhibition of D4Ertd22e if it is involved in the same cellular processes. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $182.00 | 25 | |
KN-93 inhibits CaMKII, which can influence various signaling pathways. If D4Ertd22e is involved in these pathways, functional inhibition could be indirectly achieved. | ||||||