Date published: 2025-10-15

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Cytokeratin 75 Activators

Cytokeratin 75 (KRT75) Activators encompass a group of chemical compounds that play crucial roles in enhancing the functional activity of Cytokeratin 75, primarily in the context of skin structure and integrity. Lithocholic Acid directly interacts with specific receptors, initiating signaling pathways that promote keratinocyte differentiation and elevate Cytokeratin 75 expression. Similarly, Calcitriol, through vitamin D receptors, indirectly activates Cytokeratin 75, contributing to its increased functional activity by regulating genes involved in keratinocyte differentiation.

Retinoic Acid directly enhances Cytokeratin 75 by binding to retinoic acid receptors, promoting keratinocyte differentiation and bolstering Cytokeratin 75 expression. Transforming Growth Factor Beta 1 (TGF-β1) plays an indirect but significant role in activating Cytokeratin 75, as it is known to promote keratinocyte differentiation and tissue remodeling, enhancing Cytokeratin 75's role in the skin. EGF directly stimulates Cytokeratin 75 activity by binding to its receptors on keratinocytes, leading to cell proliferation, differentiation, and increased Cytokeratin 75 expression.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lithocholic acid

434-13-9sc-215262
sc-215262A
10 g
25 g
$83.00
$272.00
1
(1)

Lithocholic Acid directly enhances the functional activity of Cytokeratin 75 by binding to specific receptors and initiating signaling cascades that promote keratinocyte differentiation and Cytokeratin 75 expression.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$325.00
$632.00
$1428.00
$2450.00
$400.00
32
(2)

Calcitriol indirectly activates Cytokeratin 75 by binding to vitamin D receptors, which regulate genes involved in keratinocyte differentiation and contribute to the increased expression and functional activity of Cytokeratin 75.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic Acid directly enhances Cytokeratin 75 activity by binding to retinoic acid receptors, thereby promoting the differentiation and function of keratinocytes and leading to an upregulation of Cytokeratin 75 expression.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$45.00
5
(1)

Ascorbic Acid indirectly activates Cytokeratin 75 by modulating collagen synthesis and promoting a microenvironment conducive to keratinocyte differentiation, thereby enhancing Cytokeratin 75's role in skin structural integrity.

Lycopene

502-65-8sc-205738
sc-205738A
sc-205738B
1 mg
5 mg
1 g
$143.00
$571.00
$6125.00
4
(1)

Lycopene directly enhances Cytokeratin 75 activity by acting as an antioxidant and protecting keratinocytes from oxidative damage, which helps maintain the functional integrity of Cytokeratin 75 in the skin.

Zinc

7440-66-6sc-213177
100 g
$47.00
(0)

Zn2+ indirectly activates Cytokeratin 75 by participating in various enzymatic reactions and cellular processes essential for keratinocyte differentiation and the maintenance of Cytokeratin 75 function in the epidermis.

Vitamin A

68-26-8sc-280187
sc-280187A
1 g
10 g
$377.00
$2602.00
(2)

Retinol directly enhances Cytokeratin 75 activity by binding to cellular retinol-binding proteins and contributing to keratinocyte differentiation, ultimately leading to increased expression and functional activity of Cytokeratin 75.

Hyaluronic acid

9004-61-9sc-337865
10 mg
$204.00
(0)

Hyaluronic Acid indirectly activates Cytokeratin 75 by contributing to skin hydration and homeostasis, creating an optimal microenvironment for keratinocyte differentiation and the functional activity of Cytokeratin 75 in maintaining skin integrity.

Hydroquinone

123-31-9sc-204773
sc-204773A
sc-204773B
250 g
1 kg
5 kg
$36.00
$91.00
$392.00
(1)

Hydroquinone directly enhances Cytokeratin 75 activity by inhibiting melanin synthesis in melanocytes, which indirectly affects keratinocyte differentiation and leads to increased expression and function of Cytokeratin 75 in the skin.