Date published: 2026-1-9

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Cyclophilin C Activators

Cyclophilin C Activators represent a class of chemical compounds carefully chosen to either directly enhance the functional activity of Cyclophilin C (PPIC) or indirectly activate it through specific signaling pathways and biological processes. Among these activators, Cyclosporin A and Sanglifehrin A directly interact with Cyclophilin C, forming complexes that modulate the calcium-regulated mitochondrial permeability transition pore. This modulation enhances various cellular functions associated with Cyclophilin C. Alisporivir (Debio 025) and NIM811 indirectly activate Cyclophilin C by binding to the same site as Cyclosporin A, improving mitochondrial function and cellular processes mediated by Cyclophilin C.

Mevalonolactone and Kinetin work by influencing the mevalonate pathway, indirectly enhancing cellular functions governed by Cyclophilin C. Methyl Jasmonate and TRO19622 also impact Cyclophilin C indirectly by regulating the mevalonate pathway and mitochondrial function, respectively. Agomelatine enhances Cyclophilin C by regulating mitochondrial function, while Mitotane (Lysodren) indirectly affects mitochondrial function, both leading to improved cellular processes associated with Cyclophilin C. Finally, 2-Hydroxypropyl-β-cyclodextrin indirectly activates Cyclophilin C by modulating lipid homeostasis, thereby impacting cellular functions related to Cyclophilin C activity. These Cyclophilin C Activators provide valuable tools for researchers studying the roles of Cyclophilin C in various cellular processes, offering precise means to enhance its activity and gain deeper insights into its functional mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Cyclosporin A

59865-13-3sc-3503
sc-3503-CW
sc-3503A
sc-3503B
sc-3503C
sc-3503D
100 mg
100 mg
500 mg
10 g
25 g
100 g
$63.00
$92.00
$250.00
$485.00
$1035.00
$2141.00
69
(5)

Cyclosporin A directly enhances Cyclophilin C's activity by forming a complex that modulates the calcium-regulated mitochondrial permeability transition pore, affecting various cellular functions related to Cyclophilin C.

Kinetin

525-79-1sc-207780
sc-207780A
1 g
5 g
$38.00
$48.00
(0)

Kinetin enhances Cyclophilin C by influencing the mevalonate pathway, which indirectly impacts cellular functions governed by Cyclophilin C.

(±)-Methyl Jasmonate

39924-52-2sc-205386
sc-205386A
sc-205386B
sc-205386C
sc-205386D
sc-205386E
sc-205386F
1 g
5 g
10 g
50 g
100 g
500 g
1 kg
$36.00
$105.00
$204.00
$890.00
$1671.00
$7081.00
$12491.00
(1)

Methyl Jasmonate indirectly activates Cyclophilin C by modulating the mevalonate pathway, leading to improved cellular processes where Cyclophilin C is involved.

Agomelatine

138112-76-2sc-207266
10 mg
$133.00
2
(1)

Agomelatine enhances Cyclophilin C activity by regulating mitochondrial function, leading to improved cellular processes associated with Cyclophilin C.

TRO 19622

22033-87-0sc-204356
sc-204356A
10 mg
50 mg
$119.00
$468.00
1
(1)

TRO19622 indirectly activates Cyclophilin C by influencing mitochondrial function, facilitating improved cellular processes where Cyclophilin C plays a pivotal role.

Mitotane

53-19-0sc-205754
sc-205754A
100 mg
1 g
$72.00
$166.00
1
(1)

Mitotane, or Lysodren, enhances Cyclophilin C activity by indirectly affecting mitochondrial function, leading to improved cellular processes associated with Cyclophilin C.

2-Hydroxypropyl-β-cyclodextrin

128446-35-5sc-203461
sc-203461B
sc-203461C
sc-203461A
1 g
100 g
500 g
5 g
$53.00
$620.00
$1989.00
$133.00
8
(1)

2-Hydroxypropyl-β-cyclodextrin indirectly activates Cyclophilin C by modulating lipid homeostasis, impacting cellular functions related to Cyclophilin C activity.