Cyclophilin C Activators represent a class of chemical compounds carefully chosen to either directly enhance the functional activity of Cyclophilin C (PPIC) or indirectly activate it through specific signaling pathways and biological processes. Among these activators, Cyclosporin A and Sanglifehrin A directly interact with Cyclophilin C, forming complexes that modulate the calcium-regulated mitochondrial permeability transition pore. This modulation enhances various cellular functions associated with Cyclophilin C. Alisporivir (Debio 025) and NIM811 indirectly activate Cyclophilin C by binding to the same site as Cyclosporin A, improving mitochondrial function and cellular processes mediated by Cyclophilin C.
Mevalonolactone and Kinetin work by influencing the mevalonate pathway, indirectly enhancing cellular functions governed by Cyclophilin C. Methyl Jasmonate and TRO19622 also impact Cyclophilin C indirectly by regulating the mevalonate pathway and mitochondrial function, respectively. Agomelatine enhances Cyclophilin C by regulating mitochondrial function, while Mitotane (Lysodren) indirectly affects mitochondrial function, both leading to improved cellular processes associated with Cyclophilin C. Finally, 2-Hydroxypropyl-β-cyclodextrin indirectly activates Cyclophilin C by modulating lipid homeostasis, thereby impacting cellular functions related to Cyclophilin C activity. These Cyclophilin C Activators provide valuable tools for researchers studying the roles of Cyclophilin C in various cellular processes, offering precise means to enhance its activity and gain deeper insights into its functional mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $63.00 $92.00 $250.00 $485.00 $1035.00 $2141.00 | 69 | |
Cyclosporin A directly enhances Cyclophilin C's activity by forming a complex that modulates the calcium-regulated mitochondrial permeability transition pore, affecting various cellular functions related to Cyclophilin C. | ||||||
Kinetin | 525-79-1 | sc-207780 sc-207780A | 1 g 5 g | $38.00 $48.00 | ||
Kinetin enhances Cyclophilin C by influencing the mevalonate pathway, which indirectly impacts cellular functions governed by Cyclophilin C. | ||||||
(±)-Methyl Jasmonate | 39924-52-2 | sc-205386 sc-205386A sc-205386B sc-205386C sc-205386D sc-205386E sc-205386F | 1 g 5 g 10 g 50 g 100 g 500 g 1 kg | $36.00 $105.00 $204.00 $890.00 $1671.00 $7081.00 $12491.00 | ||
Methyl Jasmonate indirectly activates Cyclophilin C by modulating the mevalonate pathway, leading to improved cellular processes where Cyclophilin C is involved. | ||||||
Agomelatine | 138112-76-2 | sc-207266 | 10 mg | $133.00 | 2 | |
Agomelatine enhances Cyclophilin C activity by regulating mitochondrial function, leading to improved cellular processes associated with Cyclophilin C. | ||||||
TRO 19622 | 22033-87-0 | sc-204356 sc-204356A | 10 mg 50 mg | $119.00 $468.00 | 1 | |
TRO19622 indirectly activates Cyclophilin C by influencing mitochondrial function, facilitating improved cellular processes where Cyclophilin C plays a pivotal role. | ||||||
Mitotane | 53-19-0 | sc-205754 sc-205754A | 100 mg 1 g | $72.00 $166.00 | 1 | |
Mitotane, or Lysodren, enhances Cyclophilin C activity by indirectly affecting mitochondrial function, leading to improved cellular processes associated with Cyclophilin C. | ||||||
2-Hydroxypropyl-β-cyclodextrin | 128446-35-5 | sc-203461 sc-203461B sc-203461C sc-203461A | 1 g 100 g 500 g 5 g | $53.00 $620.00 $1989.00 $133.00 | 8 | |
2-Hydroxypropyl-β-cyclodextrin indirectly activates Cyclophilin C by modulating lipid homeostasis, impacting cellular functions related to Cyclophilin C activity. | ||||||