cyclin K Inhibitors
The chemical class of Cyclin K Inhibitors includes a variety of compounds that can potentially suppress or modulate the expression and activity of Cyclin K. This class encompasses CDK inhibitors such as Flavopiridol, Palbociclib, Roscovitine, and Seliciclib, which specifically target the cell cycle regulatory machinery and can indirectly affect Cyclin K.
Compounds like Curcumin, with its broad spectrum of biological activities, and targeted inhibitors such as Rapamycin (mTOR inhibitor), LY294002 (PI3K inhibitor), and U0126 (MEK/ERK inhibitor), are included for their potential impact on pathways associated with Cyclin K. Sorafenib and Nilotinib, known for their effects on multiple signaling pathways, are also considered due to their potential to impact Cyclin K expression and activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $317.00 | ||
A cyclin-dependent kinase (CDK) inhibitor that can affect the activity of proteins like Cyclin K which are involved in cell cycle regulation. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
Another CDK inhibitor, specifically targeting CDK4 and CDK6, which can indirectly inhibit Cyclin K activity by disrupting its associated cellular pathways. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
A potent inhibitor of CDKs, known to modulate cell cycle progression, potentially affecting Cyclin K. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can affect various cellular processes, potentially including pathways related to Cyclin K. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor that can affect various cellular signaling pathways, potentially including those associated with Cyclin K. | ||||||
Sorafenib | 284461-73-0 | sc-220125 sc-220125A sc-220125B | 5 mg 50 mg 500 mg | $57.00 $100.00 $250.00 | 129 | |
A kinase inhibitor used in cancer therapy, which can affect multiple signaling pathways and potentially inhibit Cyclin K. | ||||||
Nilotinib | 641571-10-0 | sc-202245 sc-202245A | 10 mg 25 mg | $209.00 $413.00 | 9 | |
A tyrosine kinase inhibitor, known to affect various signaling pathways, potentially influencing Cyclin K activity. | ||||||