Date published: 2025-12-10

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CUL-4 Antibodies

Santa Cruz Biotechnology features a diverse variety of CUL-4 monoclonal antibodies for research focused on understanding CUL-4 function. CUL-4 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CUL-4 functions as a key component of the cullin-RING E3 ubiquitin ligase complex, which plays a significant role in regulating protein degradation and maintaining cellular homeostasis. CUL-4 participates in various cellular processes, including DNA repair, cell cycle regulation, and response to stress, making it essential for normal cellular function and development. Research has shown that CUL-4 dysregulation is linked to several diseases, including cancer, highlighting its importance as a target for therapeutic intervention. Understanding CUL-4's molecular mechanisms and cellular functions can provide valuable insights into disease pathways and potential treatment strategies. Investigating CUL-4's role in protein degradation pathways may reveal new therapeutic approaches for various pathological conditions. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of CUL-4's role in health and disease, contributing to the development of new therapeutic strategies.

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CUL-4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CUL-4 Antibody (H-11)

sc-377188mouse IgG1 κ536-597 (h)WB, IP, IF, ELISAm, r, h
12
(5)

CUL-4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-4A CRISPR/Cas9 KO Plasmid (h)

sc-401967hGene KnockoutGFP0
(0)

CUL-4A CRISPR/Cas9 KO Plasmid (h2)

sc-401967-KO-2hGene KnockoutGFP0
(0)

CUL-4A HDR Plasmid (h2)

sc-401967-HDR-2hHomology Directed RepairPuromycin0
(0)

CUL-4A Double Nickase Plasmid (h)

sc-401967-NIChGene KnockoutPuromycin0
(0)

CUL-4A Double Nickase Plasmid (h2)

sc-401967-NIC-2hGene KnockoutPuromycin0
(0)

CUL-4A CRISPR/Cas9 KO Plasmid (m)

sc-430261mGene KnockoutGFP0
(0)

CUL-4A HDR Plasmid (m)

sc-430261-HDRmHomology Directed RepairPuromycin0
(0)

CUL-4A Double Nickase Plasmid (m)

sc-430261-NICmGene KnockoutPuromycin0
(0)

CUL-4A Double Nickase Plasmid (m2)

sc-430261-NIC-2mGene KnockoutPuromycin0
(0)

CUL-4B CRISPR/Cas9 KO Plasmid (h2)

sc-402280-KO-2hGene KnockoutGFP0
(0)

CUL-4B HDR Plasmid (h2)

sc-402280-HDR-2hHomology Directed RepairPuromycin0
(0)

CUL-4B Double Nickase Plasmid (h)

sc-402280-NIChGene KnockoutPuromycin0
(0)

CUL-4B Double Nickase Plasmid (h2)

sc-402280-NIC-2hGene KnockoutPuromycin0
(0)

CUL-4B CRISPR/Cas9 KO Plasmid (m)

sc-428386mGene KnockoutGFP0
(0)

CUL-4B HDR Plasmid (m)

sc-428386-HDRmHomology Directed RepairPuromycin0
(0)

CUL-4B Double Nickase Plasmid (m)

sc-428386-NICmGene KnockoutPuromycin0
(0)

CUL-4B Double Nickase Plasmid (m2)

sc-428386-NIC-2mGene KnockoutPuromycin0
(0)

CUL-4 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-4A CRISPR Activation Plasmid (h)

sc-401967-ACThGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A CRISPR Activation Plasmid (h2)

sc-401967-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A Lentiviral Activation Particles (h)

sc-401967-LAChGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A Lentiviral Activation Particles (h2)

sc-401967-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A CRISPR Activation Plasmid (m)

sc-430261-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A CRISPR Activation Plasmid (m2)

sc-430261-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A Lentiviral Activation Particles (m)

sc-430261-LACmGene ActivationPuro, Blast, Hygro0
(0)

CUL-4A Lentiviral Activation Particles (m2)

sc-430261-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B CRISPR Activation Plasmid (h)

sc-402280-ACThGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B CRISPR Activation Plasmid (h2)

sc-402280-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B Lentiviral Activation Particles (h)

sc-402280-LAChGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B Lentiviral Activation Particles (h2)

sc-402280-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B CRISPR Activation Plasmid (m)

sc-428386-ACTmGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B CRISPR Activation Plasmid (m2)

sc-428386-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B Lentiviral Activation Particles (m)

sc-428386-LACmGene ActivationPuro, Blast, Hygro0
(0)

CUL-4B Lentiviral Activation Particles (m2)

sc-428386-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

CUL-4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-4A siRNA (h)

sc-44355hGene SilencingN/A
4
(0)

CUL-4A shRNA Plasmid (h)

sc-44355-SHhGene SilencingPuromycin
4
(0)

CUL-4A shRNA (h) Lentiviral Particles

sc-44355-VhGene SilencingPuromycin
4
(0)

CUL-4A siRNA (m)

sc-60470mGene SilencingN/A
1
(0)

CUL-4A shRNA Plasmid (m)

sc-60470-SHmGene SilencingPuromycin
1
(0)

CUL-4A shRNA (m) Lentiviral Particles

sc-60470-VmGene SilencingPuromycin
1
(0)

CUL-4B siRNA (h)

sc-37572hGene SilencingN/A
1
(0)

CUL-4B shRNA Plasmid (h)

sc-37572-SHhGene SilencingPuromycin
1
(0)

CUL-4B shRNA (h) Lentiviral Particles

sc-37572-VhGene SilencingPuromycin
1
(0)

CUL-4B siRNA (m)

sc-155877mGene SilencingN/A0
(0)

CUL-4B shRNA Plasmid (m)

sc-155877-SHmGene SilencingPuromycin0
(0)

CUL-4B shRNA (m) Lentiviral Particles

sc-155877-VmGene SilencingPuromycin0
(0)