Date published: 2026-4-25

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CUL-1 Antibodies

Santa Cruz Biotechnology delivers a wide array of CUL-1 monoclonal antibodies for various research applications. Validated applications include western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CUL-1, a key component of the SCF (Skp1-Cullin-F-box) ubiquitin ligase complex, plays a crucial role in regulating protein degradation and cell cycle progression. Through mediating the ubiquitination of target proteins, CUL-1 maintains cellular homeostasis and influences various signaling pathways. The involvement of CUL-1 in cancer biology has sparked significant interest among researchers studying disease mechanisms. Understanding CUL-1's function in developmental processes continues to reveal new insights about cellular regulation. Investigating CUL-1's role in protein degradation pathways helps advance knowledge about cell cycle control and disease progression. Research utilizing Santa Cruz Biotechnology monoclonal antibodies for CUL-1 detection contributes to advancing scientific understanding of cellular processes and disease mechanisms.

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CUL-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

CUL-1 Antibody (D-5)

sc-17775mouse IgG2a κ57-269 (h)WB, IP, IF, IHC(P), ELISAm, r, h
61
(13)

CUL-1 Antibody (AS97)

sc-12761mouse IgG2a κ(h)WB, IPm, r, h
9
(5)

CUL-1 Antibody (19)

sc-135874mouse IgG156-246 (m)WB, IPm, r, h and canine
2
(1)

CUL-1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-1 CRISPR/Cas9 KO Plasmid (h)

sc-400972hGene KnockoutGFP0
(0)

CUL-1 HDR Plasmid (h)

sc-400972-HDRhHomology Directed RepairPuromycin0
(0)

CUL-1 Double Nickase Plasmid (h)

sc-400972-NIChGene KnockoutPuromycin0
(0)

CUL-1 Double Nickase Plasmid (h2)

sc-400972-NIC-2hGene KnockoutPuromycin0
(0)

CUL-1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-1 CRISPR Activation Plasmid (h)

sc-400972-ACThGene ActivationPuro, Blast, Hygro0
(0)

CUL-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

CUL-1 siRNA (h)

sc-35126hGene SilencingN/A
4
(0)

CUL-1 shRNA Plasmid (h)

sc-35126-SHhGene SilencingPuromycin
4
(0)

CUL-1 shRNA (h) Lentiviral Particles

sc-35126-VhGene SilencingPuromycin
4
(0)

CUL-1 siRNA (m)

sc-35127mGene SilencingN/A
1
(0)

CUL-1 shRNA Plasmid (m)

sc-35127-SHmGene SilencingPuromycin
1
(0)

CUL-1 shRNA (m) Lentiviral Particles

sc-35127-VmGene SilencingPuromycin
1
(0)